2-(2,3,4,5-tetrafluorophenyl)-1H-imidazo[4,5-b]phenazine | 1431328-08-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 2-(2,3,4,5-tetrafluorophenyl)-1H-imidazo[4,5-b]phenazine
• CAS: 1431328-08-3
• 化学式: C₁₉H₈F₄N₄
• 分子量: 368.293
• InChiKey: WDFJPCCIWONTOH-UHFFFAOYSA-N

物化性质

• 沸点：
  586.4±60.0 °C(predicted)
• 密度：
  1.588±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.88
• 重原子数：
  27.0
• 可旋转键数：
  1.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  54.46
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  2-(2,3,4,5-tetrafluorophenyl)-1H-imidazo[4,5-b]phenazine 、 四丁基氟化铵 以 乙腈 为溶剂， 生成
  参考文献：
  名称：

  A novel heteroacene, 2-(2,3,4,5-tetrafluorophenyl)-1H-imidazo[4,5-b]phenazine as a multi-response sensor for F− detection

  摘要：

  A novel heteroacene, 2-(2,3,4,5-tetrafluorophenyl)-1H-imidazo[4,5-b]phenazine has been successfully synthesized. The heteroacene can selectively detect F- over Cl-, Br-, I-, NO3-, HSO4-, ClO4-, and BF4- in organic solvents through colorimetric and fluorescent responses. The interaction between the heteroacene and F- was investigated through UV-Vis, fluorescence, and H-1 NMR titration experiments, which suggested that the effects might occur via a combined process including hydrogen bond, deprotonation, and anion-pi interactions between the sensor and F-. (c) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.03.030
• 作为产物：
  描述：

  3,4,5,6-四氟苯酐 、 2,3-二氨基吩嗪 在 zinc diacetate 作用下， 反应 12.0h， 以19%的产率得到2-(2,3,4,5-tetrafluorophenyl)-1H-imidazo[4,5-b]phenazine
  参考文献：
  名称：

  A novel heteroacene, 2-(2,3,4,5-tetrafluorophenyl)-1H-imidazo[4,5-b]phenazine as a multi-response sensor for F− detection

  摘要：

  A novel heteroacene, 2-(2,3,4,5-tetrafluorophenyl)-1H-imidazo[4,5-b]phenazine has been successfully synthesized. The heteroacene can selectively detect F- over Cl-, Br-, I-, NO3-, HSO4-, ClO4-, and BF4- in organic solvents through colorimetric and fluorescent responses. The interaction between the heteroacene and F- was investigated through UV-Vis, fluorescence, and H-1 NMR titration experiments, which suggested that the effects might occur via a combined process including hydrogen bond, deprotonation, and anion-pi interactions between the sensor and F-. (c) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.03.030