3-cyclohexyl-5-methyl-oxazolidine-2,4-dione | 104398-25-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 3-cyclohexyl-5-methyl-oxazolidine-2,4-dione
• 英文别名: 3-Cyclohexyl-5-methyl-oxazolidin-2,4-dion；3-Cyclohexyl-5-methyl-1,3-oxazolidine-2,4-dione
• CAS: 104398-25-6
• 化学式: C₁₀H₁₅NO₃
• 分子量: 197.234
• InChiKey: JWPQUJSIVUXIIB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  46.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-cyclohexyl-5-methyl-oxazolidine-2,4-dione 、 苄胺 反应 5.0h， 以59%的产率得到N-(benzylcarbamoyl)-N-cyclohexyl-2-hydroxypropanamide
  参考文献：
  名称：

  Facile Synthesis of 3-Alkyl-5-methyloxazolidine-2,4-diones and N-Lactoyl-N,N′-dialkylureas

  摘要：

  [image omitted] The reaction between aliphatic amines and propylene carbonate can be performed in solventless conditions under microwave irradiation, becoming nearly complete within 15min of irradiation. Oxidation of the formed mixture of 2-hydroxyethylcarbamates gives 3,5-methylalkyl-oxazolidine-2,4-diones. These compounds can react further with aliphatic primary amines to give N-lactoylureas.

  DOI：

  10.1080/00397911003707154
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 3-cyclohexyl-5-methyl-oxazolidine-2,4-dione
  参考文献：
  名称：

  N-Substituted Oxazolidinediones

  摘要：

  DOI：

  10.1021/ja01533a042