zinc (1,4,7,10-tetraoxacyclododecan-2-yl)methyl 3-deformyl-3-hydroxymethylpyropheophorbide d | 1430855-16-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: zinc (1,4,7,10-tetraoxacyclododecan-2-yl)methyl 3-deformyl-3-hydroxymethylpyropheophorbide d
• CAS: 1430855-16-5；1431108-48-3
• 化学式: C₄₁H₄₈N₄O₈Zn
• 分子量: 790.244
• InChiKey: UXPVSJKLLSURJP-NHVVTPCFSA-M

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  (1,4,7,10-tetraoxacyclododecan-2-yl)methyl 3-deformyl-3-hydroxymethylpyropheophorbide d 、 zinc(II) acetate dihydrate 以 甲醇 、 氯仿 为溶剂， 以97%的产率得到zinc (1,4,7,10-tetraoxacyclododecan-2-yl)methyl 3-deformyl-3-hydroxymethylpyropheophorbide d
  参考文献：
  名称：

  Synthesis and self-assembly of amphiphilic zinc chlorophyll derivatives possessing a crown ether at the 17-propionate residue

  摘要：

  Zinc 3(1)-hydroxy-13(1)-oxo-chlorins 1-3 possessing a 12-crown-4, 15-crown-5, and 18-crown-6 ether at the 17-propionate residue were synthesized and self-assembled in aqueous and non-polar organic media. Zn chlorins 1-3 exhibited red-shifted Q(y) absorption bands and large CD signals around 730 nm in an aqueous solution after standing for 2 h or 2 days, indicating the formation of their oligomeric self-aggregates as in chlorosomes of green photosynthetic bacteria. Incubation for 2 weeks decreased the absorption bands around 730 nm, accompanying an appearance of the absorption band around 675 nm. These show that Zn chlorins 1-3 finally formed thermodynamically stable anti-parallel dimers in the aqueous solution. 17(6)-Epimerically pure 1-3 exhibited essentially the same spectral properties as the corresponding epimeric mixtures, but larger CD signals were observed around 730 nm in the spectra of epimerically pure 1 and 2 after standing for 2 h or 2 days than those of their epimeric mixtures. In a non-polar organic solvent, Zn chlorins 1-3 formed less time-dependent chlorosomal self-aggregates that exhibited Q(y) absorption bands around 735 nm. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.03.015