magnesium;propanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: magnesium;propanoate
• 化学式: C6H10MgO4
• 分子量: 170.45
• InChiKey: CQQJGTPWCKCEOQ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -2.09
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  80.3
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• FLUOROALKYLATING AGENT
  申请人：IHARA CHEMICAL INDUSTRY CO., LTD.

  公开号：US20170197920A1

  公开（公告）日：2017-07-13

  Problem to be Solved It is intended to provide an industrially preferable fluoroalkylating agent and use thereof. Solution The present invention provides a fluoroalkylating agent represented by the general formula (1) wherein R 1 is a C1 to C8 fluoroalkyl group; R 2 and R 3 are each independently a C1 to C12 alkyl group or the like; Y 1 to Y 4 are each independently a hydrogen atom, a halogen atom, or the like; and X − is a monovalent anion. A compound of the general formula (3): R 4 —S—R 1 having an introduced C1 to C8 fluoroalkyl group is easily obtained by reacting a compound of the general formula (2): R 4 —S—Z wherein R 4 is a hydrocarbon group or the like; and Z is a leaving group, with the compound of the general formula (1).

  要解决的问题 旨在提供一种工业上可取的氟烷基化剂及其使用方法。 解决方案 本发明提供了一种由通式（1）表示的氟烷基化剂，其中R 1 是C1到C8的氟烷基团；R 2 和R 3 分别独立地是C1到C12的烷基团或类似物；Y 1 到Y 4 分别独立地是氢原子、卤素原子或类似物；X − 是一价阴离子。 通式（3）的化合物：R 4 —S—R 1 ，其中引入了C1到C8的氟烷基团，可通过将通式（2）的化合物：R 4 —S—Z（其中R 4 是烃基团或类似物；Z是离去基团）与通式（1）的化合物反应而轻松获得。
• [EN] TREATMENT OF INFECTIONS<br/>[FR] TRAITEMENT D'INFECTIONS
  申请人：ASCENDIS PHARMA AS

  公开号：WO2020064844A1

  公开（公告）日：2020-04-02

  The present invention relates among other aspects to a conjugate or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising said conjugate or its pharmaceutically acceptable salt for use in a method of preventing or treating an infection, wherein said conjugate is water-insoluble and comprises a polymeric moiety -Z to which a plurality of moieties -L2-X0D-L1-D are covalently conjugated, wherein each -D is independently an antibiotic moiety; each -L1- is independently a linker moiety to which -D is covalently and reversibly conjugated; each -X0D- is independently absent or a linkage and each -L2- is independently either a chemical bond or a spacer moiety.

  本发明涉及一种共轭物或其药用可接受的盐，或包含所述共轭物或其药用可接受的盐的药物组合物，用于预防或治疗感染的方法，其中所述共轭物不溶于水，包括一个聚合物基团-Z，其中多个基团-L2-X0D-L1-D以共价结合方式共轭，其中每个-D独立地是抗生素基团；每个-L1-独立地是连接基团，与-D以共价和可逆方式结合；每个-X0D-独立地不存在或是一个连接，每个-L2-独立地是化学键或间隔基团。
• [EN] DISUBSTITUTED DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS<br/>[FR] COMPOSÉS DISUBSTITUÉS DE DIARYLOXYBENZOHÉTÉRODIAZOLE
  申请人：ENI SPA

  公开号：WO2016046319A1

  公开（公告）日：2016-03-31

  Disubstituted diaryloxybenzoheterodiazole compound of general formula (1): in which: ∙ - Z represents a sulfur atom, an oxygen atom, a selenium atom; or an NR 5group in which R5 is selected from linear or branched C1-C20, preferably C1-C8, alkyl groups, or from optionally substituted aryl groups; ∙ - R1, R2 and R3 are as defined in the claims. The said disubstituted diaryloxybenzoheterodiazole compound of general formula (I) can advantageously be used as a spectrum converter in luminescent solar concentrators (LSCs) which are in turn capable of improving the performance of photovoltaic devices (or solar devices) selected, for example, from photovoltaic cells (or solar cells), photovoltaic modules (or solar modules) on either a rigid substrate or a flexible substrate.

  通用公式（1）的二取代二芳氧基苯并噻二唑化合物：其中：∙ - Z代表硫原子、氧原子、硒原子；或者一个NR 5基团，其中R5从线性或支链的C1-C20，优选C1-C8，烷基基团中选择，或者从可选择取代的芳基基团中选择；∙ - R1、R2和R3如权利要求中所定义。所述的通用公式（I）的二取代二芳氧基苯并噻二唑化合物可以优点地用作光致发光太阳能聚光器（LSCs）中的光谱转换器，这反过来能够改善选定的光伏器件（或太阳能器件）的性能，例如光伏电池（或太阳能电池）、光伏模块（或太阳能模块）在刚性基板或柔性基板上。
• 7-METHYL-3-METHYLENE-7-OCTENYL HALIDE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 7-METHYL-3-METHYLENE-7-OCTENYL PROPIONATE
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：US20160185690A1

  公开（公告）日：2016-06-30

  Provided is a simple, selective and efficient method for producing 7-methyl-3-methylene-7-octenyl propionate and the like. More specifically, provided is, for example, a method for producing 7-methyl-3-methylene-7-octenyl propionate, comprising the steps of: subjecting a nucleophile represented by Formula (1) and an electrophile represented by Formula (2) to a coupling reaction to obtain a 7-methyl-3-methylene-7-octenyl halide represented by Formula (3), and subjecting the 7-methyl-3-methylene-7-octenyl halide (3) to propionyloxylation to obtain the 7-methyl-3-methylene-7-octenyl propionate represented by Formula (4).

  提供了一种简单、选择性和高效的方法，用于生产7-甲基-3-亚甲基-7-辛烯基丙酸酯等物质。更具体地说，例如提供了一种生产7-甲基-3-亚甲基-7-辛烯基丙酸酯的方法，包括以下步骤：将由式（1）表示的亲核试剂和由式（2）表示的亲电试剂进行偶联反应，得到由式（3）表示的7-甲基-3-亚甲基-7-辛烯基卤代物，然后将7-甲基-3-亚甲基-7-辛烯基卤代物（3）进行丙酰氧化反应，得到由式（4）表示的7-甲基-3-亚甲基-7-辛烯基丙酸酯。
• USE OF DICYCLOHEXYLMETHANOL DERIVATIVES HAVING ANTIMICROBIAL PROPERTIES
  申请人：MERCK PATENT GmbH

  公开号：US20150118172A1

  公开（公告）日：2015-04-30

  The present invention relates to the use of at least one dicyclohexylmethanol derivative of the formula (I) as antimicrobial active compound or as anti-acne, antidandruff, deodorant or antiperspirant active compound, to preparations comprising these compounds, and to specific dicyclohexylmethanol derivatives and to a process for the preparation thereof.

  本发明涉及将式(I)的至少一种二环己基甲醇衍生物用作抗微生物活性化合物或用作抗痘、抗头皮屑、除臭剂或止汗剂活性化合物，以及含有这些化合物的制剂，以及特定的二环己基甲醇衍生物及其制备方法。