3-pentoxypropanoyl chloride | 114953-18-3

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: 3-pentoxypropanoyl chloride
• 英文别名: β-n-Amyloxypropionylchlorid
• CAS: 114953-18-3
• 化学式: C₈H₁₅ClO₂
• 分子量: 178.659
• InChiKey: YYCQICJWXMKYCU-UHFFFAOYSA-N

物化性质

• 沸点：
  82-84 °C(Press: 6 Torr)
• 密度：
  1.0151 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.35
• 重原子数：
  11.0
• 可旋转键数：
  7.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  26.3
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  3-pentoxypropanoyl chloride 在 氢氟酸 作用下， 生成 tetrafluoro-3-(undecafluoro-pentyloxy)-propionyl fluoride
  参考文献：
  名称：

  Fluorocarbon acids and derivatives

  摘要：

  公开号：

  US02713593A1

文献信息

• Potential long-acting contraceptive agents: Esters of testosterone with alkoxy- and halogeno-substituted carboxylic acids
  作者：A. Shafiee、M. Vosooghi、C.G. Francisco、R. Freire、R. Hernandez、J.A. Salazar、E. Suarez、S. Sotheeswaran、A.A.L Gunatilaka

  DOI：10.1016/0039-128x(87)90013-4

  日期：1987.4

  The chemical synthesis and physical data of several new esters of testosterone (17 beta-hydroxyandrost-4-en-3-one), which contain either a halogeno or an alkoxy substituent in the acid chain, are reported.
• Long-acting contraceptive agents: Esters of norethisterone with alkoxy- and halogeno-substituted carboxylic acids
  作者：A. Shafiee、M. Vossoghi、C.G. Francisco、R. Freire、R. Hernandez、J.A. Salazar、E. Suarez、S. Sotheeswaran

  DOI：10.1016/0039-128x(83)90099-5

  日期：1983.3

  The chemical synthesis and physical data of several new esters of norethisterone (17 alpha-ethynyl-17 beta-hydroxyestr-4-en-3-one) are reported, which contain either a chloro- or an alkoxy-group as a substituent in the acid side-chain.
• Weizmann; Stephen; Agashe, Journal of the Chemical Society, 1913, vol. 103, p. 1857
  作者：Weizmann、Stephen、Agashe

  DOI：——

  日期：——
• Weizmann; Stephen; Agashe, Journal of the Chemical Society, 1913, vol. 103, p. 1860
  作者：Weizmann、Stephen、Agashe

  DOI：——

  日期：——
• The influence of heteroatoms and branchings on the liquid-crystalline properties of cyclotriveratrylene derivatives
  作者：Hansjörg Budig、Ralph Lunkwitz、Reinhard Paschke、Carsten Tschierske、Ulrich Nütz、Siegmar Diele、Gerhard Pelzl

  DOI：10.1039/jm9960601283

  日期：——

  The synthesis and properties of novel pyramidic liquid crystals are reported. 2,3,7,8,12,13-Hexaacyloxy-10, 15-dihydro-5H-tribenzo [a,d,g]cyclononenes incorporate heteroatoms (O or S) in different positions in the lateral chains. The mesomorphic properties of these compounds were investigated by polarizing light microscopy, calorimetry and X-ray scattering. Most of the compounds display broad ranges of different columnar mesophases (D-hd, D-rd, D-ob). It was found that the mesophase stability of the 3-oxaalkanoates is increased in comparison to the analogous alkanoates. However, the shift of the oxygen atoms into the 4 positions leads to a destabilization of the mesophases. The 3-thiaalkanoate displays approximately the same clearing temperature as the corresponding carbon analogue. Branching of the lateral chains gives rise to discotic liquid crystals with broad mesomorphic ranges and increased clearing temperatures, compared to the corresponding non-branched derivatives.