6-{2-[(4-Amino-4-carboxybutyl)amino]-4H-imidazo[4,5-b]pyridin-4-yl}norleucine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 6-{2-[(4-Amino-4-carboxybutyl)amino]-4H-imidazo[4,5-b]pyridin-4-yl}norleucine
• 英文别名: 2-amino-6-[2-[(4-amino-4-carboxybutyl)amino]imidazo[4,5-b]pyridin-4-yl]hexanoic acid
• 化学式: C₁₇H₂₆N₆O₄
• 分子量: 378.4
• InChiKey: AYEKKSTZQYEZPU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.7
• 重原子数：
  27
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  169
• 氢给体数：
  5
• 氢受体数：
  9

文献信息

• NOVEL ENZYME AND METHOD FOR ASSAYING PENTOSIDINE USING SAME
  申请人：Kikkoman Corporation

  公开号：EP3760724A1

  公开（公告）日：2021-01-06

  The present invention provides a protein having pentosidine oxidase activity, a method for measuring pentosidine comprising: contacting the protein with a specimen; and detecting a change caused by the contact, and the like.

  本发明提供了一种具有戊苷氧化酶活性的蛋白质，一种测量戊苷的方法，包括：将该蛋白质与试样接触；以及检测由接触引起的变化等。
• METHOD FOR MEASURING PENTOSIDINE AND MEASUREMENT KIT
  申请人：Kikkoman Corporation

  公开号：EP4023754A1

  公开（公告）日：2022-07-06

  Provided is a method for measuring pentosidine in a specimen, the measurement method comprising the steps of: degrading the specimen with an amino acid degrading enzyme; contacting the specimen after the degradation step with a protein having activity that oxidatively degrades pentosidine; and detecting change resulting from the contact, wherein the amino acid degrading enzyme and the protein having activity that oxidatively degrades pentosidine are different from each other.

  本发明提供了一种测量标本中喷托西啶含量的方法，该测量方法包括以下步骤：用氨基酸降解酶降解标本；将降解步骤后的标本与具有氧化降解喷托西啶活性的蛋白质接触；以及检测接触产生的变化，其中氨基酸降解酶和具有氧化降解喷托西啶活性的蛋白质彼此不同。
• Method for Measuring Pentosidine and Measurement Kit
  申请人：Kikkoman Corporation

  公开号：US20220396822A1

  公开（公告）日：2022-12-15

  Provided is a method for measuring pentosidine in a specimen, the measurement method comprising the steps of: degrading the specimen with an amino acid degrading enzyme; contacting the specimen after the degradation step with a protein having activity that oxidatively degrades pentosidine; and detecting change resulting from the contact, wherein the amino acid degrading enzyme and the protein having activity that oxidatively degrades pentosidine are different from each other.