2-[(Octadec-9-enoyl)amino]ethane-1-sulfonic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-[(Octadec-9-enoyl)amino]ethane-1-sulfonic acid
• 英文别名: 2-(octadec-9-enoylamino)ethanesulfonic acid
• 化学式: C₂₀H₃₉NO₄S
• 分子量: 389.6
• InChiKey: KOGRJTUIKPMZEJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  26
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  91.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Methods and systems for determining autism spectrum disorder risk
  申请人：Laboratory Corporation of America Holdings

  公开号：US10041932B2

  公开（公告）日：2018-08-07

  In certain embodiments, the invention stems from the discovery that analysis of population distribution curves of metabolite levels in blood can be used to facilitate predicting risk of autism spectrum disorder (ASD) and/or to differentiate between ASD and non-ASD developmental delay (DD) in a subject. In certain aspects, information from assessment of the presence, absence, and/or direction (upper or lower) of a tail effect in a metabolite distribution curve is utilized to predict risk of ASD and/or to differentiate between ASD and DD.

  在某些实施方案中，本发明源于发现血液中代谢物水平的群体分布曲线分析可用于促进预测自闭症谱系障碍（ASD）的风险和/或区分受试者的自闭症谱系障碍和非自闭症谱系障碍发育迟缓（DD）。在某些方面，评估代谢物分布曲线中尾部效应的存在、不存在和/或方向（上部或下部）的信息可用于预测 ASD 的风险和/或区分 ASD 和 DD。
• Compositions and methods that modulate digestibility in a companion animal
  申请人：NESTEC SA

  公开号：US10624370B2

  公开（公告）日：2020-04-21

  A specific type of digestibility in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the specific type of digestibility or adjusting the diet of the animal to decrease the amount of a compound which positively or negatively modulates the specific type of digestibility. The specific type of digestibility can be one or more of organic matter digestibility, dry matter digestibility, fiber digestibility, energy digestibility, fat digestibility, or protein digestibility.

  通过调整动物的饮食，增加对特定类型消化率有积极或消极调节作用的化合物的用量，或调整动物的饮食，减少对特定类型消化率有积极或消极调节作用的化合物的用量，可以改善伴侣动物的特定类型消化率。特定类型的消化率可以是有机物消化率、干物质消化率、纤维消化率、能量消化率、脂肪消化率或蛋白质消化率中的一种或多种。
• METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION
  申请人：The Board of Regents of The University of Texas System

  公开号：EP2776829A1

  公开（公告）日：2014-09-17
• METHODS AND SYSTEMS FOR DETERMINING AUTISM SPECTRUM DISORDER RISK
  申请人：Laboratory Corporation of America Holdings

  公开号：EP3151665B1

  公开（公告）日：2021-03-10
• COMPOSITIONS AND METHODS THAT MODULATE DIGESTIBILITY IN A COMPANION ANIMAL
  申请人：Société des Produits Nestlé S.A.

  公开号：EP3554263A1

  公开（公告）日：2019-10-23