7-Amino-caprinsaeure | 102878-41-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 7-Amino-caprinsaeure
• 英文别名: 7-azaniumyldecanoate
• CAS: 102878-41-1
• 化学式: C₁₀H₂₁NO₂
• 分子量: 187.282
• InChiKey: NRKKNXXLTISZHH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-Butyryl-thienyl-(2)-essigsaeure-oxim 在 镍 作用下， 生成 7-Amino-caprinsaeure
  参考文献：
  名称：

  噻吩及其同系物作为制备脂肪族氨基酸的起始化合物

  摘要：

  已经开发了一种由噻吩及其同系物制备脂族氨基酸的方法。

  DOI：

  10.1016/0040-4020(62)80020-9

文献信息

• [EN] DRUG CONJUGATES<br/>[FR] CONJUGUÉS DE MÉDICAMENT
  申请人：UNIV MISSOURI

  公开号：WO2009158633A1

  公开（公告）日：2009-12-30

  Conjugated compounds comprising a therapeutic or diagnostic agent linked to a substrate for a cell membrane transporter or receptor by lipophilic linker are provided.

  提供了包含治疗或诊断药物与细胞膜转运体或受体的底物通过亲脂性连接剂连接的共轭化合物。
• Manufacture and use of an antibiotic/antibiotics preparation
  申请人：Heraues Kulzer GmbH & Co.KG

  公开号：US20020183265A1

  公开（公告）日：2002-12-05

  The present invention concerns the manufacture and use of an antibiotic/antibiotics preparation for human and veterinary medicine, for the treatment of local microbial infections in hard and soft tissue. The manufacture in accordance with the invention of an antibiotic/antibiotics preparation takes place according to the invention in that water, an amphiphilic component of a representative of the alkyl sulfates, aryl sulfates, alkylaryl sulfates, cycloalkyl sulfates, alkylcycloalkyl sulfates, alkyl sulfamates, cycloalkyl sulfamates, alkylcycloalkyl sulfamates, aryl sulfamates, alkylaryl sulfamates, alkyl sulfonates, fatty acid-2-sulfonates, aryl sulfonates, alkylaryl sulfonates, cycloalkyl sulfonates, cycloalkyl sulfonates, alkylcycloalkyl sulfonates, alkyl disulfates, cycloalkyl disulfates, alkyl disulfonates, cycloalkyl disulfonates, aryl disulfonates, alkylaryl disulfonates, aryl trisulfonates and alkylaryl trisulfonates, one or more antibiotic components from the group of aminoglycoside antibiotics, lincosamide antibiotics and tetracycline antibiotics, an organic auxiliary component and/or an inorganic auxiliary component and if need be at least one biologically active component are mixed together and shaped into molded elements, granulates, powders, foils, shaped masses and threads.

  本发明涉及一种用于治疗硬组织和软组织局部微生物感染的人类和兽医抗生素/抗生素制剂的制造和使用。烷基环烷基硫酸盐、烷基氨基磺酸盐、环烷基氨基磺酸盐、烷基环烷基氨基磺酸盐、芳基氨基磺酸盐、烷芳基氨基磺酸盐、烷基磺酸盐、脂肪酸-2-磺酸盐、芳基磺酸盐、烷芳基磺酸盐、环烷基磺酸盐、环烷基磺酸盐、烷基环烷基磺酸盐、烷基二硫酸盐、环烷基二硫酸盐、环烷基二硫酸盐、环烷基二硫酸盐、环烷基二硫酸盐、环烷基二硫酸盐、环烷基二硫酸盐、环烷基二硫酸盐、环烷基二硫酸盐烷基二磺酸盐、环烷基二磺酸盐、烷基二磺酸盐、环烷基二磺酸盐、芳基二磺酸盐、 烷芳基二磺酸盐、芳基三磺酸盐和烷芳基三磺酸盐； 氨基糖苷类抗生素中的一种或多种抗生素成分、林可酰胺类抗生素和四环素类抗生素中的一种或多种抗生素成分、一种有机辅助成分和/或一种无机辅助成分，必要时还包括至少一种生物活性成分。
• Antibiotic(s) preparation with retarding active ingredient release
  申请人：Heraues Kulzer GmbH & Co.KG

  公开号：US20020182251A1

  公开（公告）日：2002-12-05

  The present invention concerns an antibiotic/antibiotics preparation for resorbable and non-resorbable implants for human and veterinary medicine, for the treatment of local microbial infections in hard and soft tissue. The invented antibiotic/antibiotics preparation is a mixture consisting of at least one amphiphilic component of a representative of the alkyl sulfates, aryl sulfates, alkylaryl sulfates, cycloalkyl sulfates, alkylcycloalkyl sulfates, alkyl sulfamates, cycloalkyl sulfamates, alkylcycloalkyl sulfamates, aryl sulfamates, alkylaryl sulfamates, alkyl sulfonates, fatty acid-2-sulfonates, aryl sulfonates, alkylaryl sulfonates, cycloalkyl sulfonates, alkylcycloalkyl sulfonates, alkyl disulfates, cycloalkyl disulfates, alkyl disulfonates, cycloalkyl disulfonates, aryl disulfonates, alkylaryl disulfonates, aryl trisulfonates and alkylaryl trisulfonates as well as at least one antibiotic component from the group of aminoglycoside antibiotics, lincosamide antibiotics, 4-quinolone antibiotics and tetracycline antibiotics, and if need be at least one anhydrous organic auxiliary component and if need be at least one inorganic auxiliary component and if need be at least one biologically active component. The antibiotic/antibiotics preparation of the invention has a retarding active ingredient release.

  本发明涉及一种抗生素/抗菌剂制剂，用于人类和兽医的可吸收和不可吸收植入物，以治疗硬组织和软组织的局部微生物感染。本发明的抗生素/抗菌剂制剂是一种混合物，由烷基硫酸盐、芳基硫酸盐、烷芳基硫酸盐、环烷基硫酸盐、烷基环烷基硫酸盐、烷基氨基磺酸盐中具有代表性的至少一种两亲成分组成、环烷基氨基磺酸盐、烷基环烷基氨基磺酸盐、芳基氨基磺酸盐、烷芳基氨基磺酸盐、烷基磺酸盐、脂肪酸-2-磺酸盐、芳基磺酸盐、烷芳基磺酸盐、环烷基磺酸盐、烷基环烷基磺酸盐、烷基二硫酸盐、环烷基二磺酸盐、烷基二磺酸盐、环烷基二磺酸盐、芳基二磺酸盐、烷芳基二磺酸盐、 芳基三磺酸盐和烷芳基三磺酸盐，以及氨基糖苷类抗生素中的至少一种抗生素成分、林可酰胺类抗生素、4-喹诺酮类抗生素和四环素类抗生素中的至少一种抗生素成分，以及至少一种无水有机辅助成分（如有必要）和至少一种无机辅助成分（如有必要），以及至少一种生物活性成分（如有必要）。本发明的抗生素/抗生素制剂具有延缓活性成分释放的作用。
• Gol'dfarb,Ya.L. et al., Journal of general chemistry of the USSR, 1961, vol. 31, p. 1924 - 1929
  作者：Gol'dfarb,Ya.L. et al.

  DOI：——

  日期：——
• Drug Conjugates
  申请人：Mitra Ashim K.

  公开号：US20110105417A1

  公开（公告）日：2011-05-05

  Conjugated compounds comprising a therapeutic or diagnostic agent linked to a substrate for a cell membrane transporter or receptor by lipophilic linker are provided.