A process for producing L-ascorbic acid or D-erythorbic acid or in each case its sodium, potassium or calcium salt, from 2-keto-L-gulonic acid or 2-keto-D-gluconic acid or in each case its sodium, potassium or calcium salt, involves incubating 2-keto-L-gulonic acid or 2-keto-D-gluconic acid, each as the free acid or as its sodium, potassium or calcium salt, and cells of a thermoacidophilic microorganism at temperatures from about 30°C to about 100°C and at a pH from about 1 to about 6 in a solution to form L-ascorbic acid or D-erythorbic acid or an appropriate salt thereof, and isolating said product from the solution. L-Ascorbic acid (vitamin C) is widely used not only in health care as such but also in food, animal feed, e.g. fish feed, and cosmetics. D-erythorbic acid is mainly used as an antioxidant for food additives.
一种由
2-酮-L-古洛糖酸或2-酮-
D-葡萄糖酸或其钠盐、
钾盐或
钙盐生产L-
抗坏血酸或D-
赤藓红酸或其钠盐、
钾盐或
钙盐的工艺,包括将
2-酮-L-古洛糖酸或2-酮-
D-葡萄糖酸(各自作为
游离酸或其钠盐、
钾盐或
钙盐)与嗜热微
生物细胞在温度约为30℃至约100℃、pH值约为1至约6的溶液中孵育,形成L-
抗坏血酸或D-
赤藓红酸或其钠盐、
钾盐或
钙盐、
钾或
钙盐,以及嗜热微
生物细胞,在温度约 30°C 至约 100°C、pH 值约 1 至约 6 的溶液中形成 L-
抗坏血酸或 D-
赤霉酸或其适当的盐,并从溶液中分离出所述产品。左旋
抗坏血酸(
维生素 C)不仅广泛应用于医疗保健领域,还用于食品、动物饲料(如鱼饲料)和化妆品。D-
赤霉酸主要用作
食品添加剂的
抗氧化剂。