6-Hydroxy-7,9-octadecadiynoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-Hydroxy-7,9-octadecadiynoic acid
• 英文别名: 6-hydroxyoctadeca-7,9-diynoic acid
• 化学式: C₁₈H₂₈O₃
• 分子量: 292.4
• InChiKey: APWVQFPFWVNZPF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  21
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  6-Hydroxy-7,9-octadecadiynoic acid 生成 Methyl 6-hydroxyoctadeca-7,9-diynoate
  参考文献：
  名称：

  PATIL, ASHOK D.;CHAN, JAMES A.;LOIS-FLAMBERG, PEARI;MAYER, RUTH J.;WESTLE+, J. NATUR. PROD., 52,(1989) N, C. 153-161

  摘要：

  DOI：

文献信息

• Rice Bran Extracts for Inflammation and Methods of Use Thereof
  申请人：Alberte Randall S.

  公开号：US20090285919A1

  公开（公告）日：2009-11-19

  The present invention relates in part to stabilized rice bran extracts enriched in compounds that have inhibitory activity against certain anti-inflammatory therapeutic endpoints, such as the COX-1, COX-2 and 5-LOX enzymes. Another aspect of the invention relates to pharmaceutical compositions comprising the extracts and to methods of treating inflammatory diseases comprising administering the aforementioned extracts.
• Extracts of Cranberry and Methods of Using Thereof
  申请人：Alberte Randall S.

  公开号：US20100028469A1

  公开（公告）日：2010-02-04

  The present disclosure relates in part to extracts of cranberry ( Vaccinium macrocarpon ) comprising an enriched amount of certain compounds having anti-infective activity, e.g. antibacterial and/or antifungal activity, e.g. activity against C. albicans . Another aspect of the disclosure relates to combined cranberry and cinnamon extracts. In certain embodiments, these combined extracts have been optimized to control urinary tract infections caused by E. coli, S. aureus and C. albicans . Certain embodiments of the extract are enriched in bioactive compounds that have been shown to inhibit C. albicans adhesion and/or biofilm formation and its growth in vitro. In another aspect of the disclosure, the extracts are enriched in bioactives derived from cranberry and cinnamon that have been shown to inhibit the attachment and the growth of common urinary tract pathogens like E. coli, S. aureus and C. albicans.
• PATIL, ASHOK D.;CHAN, JAMES A.;LOIS-FLAMBERG, PEARI;MAYER, RUTH J.;WESTLE+, J. NATUR. PROD., 52,(1989) N, C. 153-161
  作者：PATIL, ASHOK D.、CHAN, JAMES A.、LOIS-FLAMBERG, PEARI、MAYER, RUTH J.、WESTLE+

  DOI：——

  日期：——