6-azaniumyl-2-[(2-azaniumyl-4-carboxylatobutanoyl)amino]hexanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 6-azaniumyl-2-[(2-azaniumyl-4-carboxylatobutanoyl)amino]hexanoate
• 化学式: C11H21N3O5
• 分子量: 275.3
• InChiKey: BBBXWRGITSUJPB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  165
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Transglutaminase inhibitors and methods of use thereof
  申请人：Khosla Chaitan

  公开号：US20090312272A1

  公开（公告）日：2009-12-17

  Transglutaminase inhibitors and methods of use thereof are provided.

  本发明提供了转麦胶原酶抑制剂及其使用方法。
• TRANSGLUTAMINASE INHIBITORS AND METHODS OF USE THEREOF
  申请人：The Board of Trustees of the Leland Stanford Junior University

  公开号：US20130102633A1

  公开（公告）日：2013-04-25

  Transglutaminase inhibitors and methods of use thereof are provided.

  本发明提供了谷氨酰胺转移酶抑制剂及其使用方法。
• Process for efficiently producing transglutaminase through DNA recombination
  申请人：Ajinomoto Co., Inc.

  公开号：EP0743365A2

  公开（公告）日：1996-11-20

  The present invention relates to a process for producing a transglutaminase, which comprises incubating Escherichia coli expressing genes encoding a heat shock protein (DnaJ) and a transglutaminase. The transglutaminase is produced in large quantities, at low cost and has the appropriate stereostructure to render the transglutaminase biologically active. The transglutaminase so produced is useful in the food industry.

  本发明涉及一种生产转谷氨酰胺酶的工艺，它包括培养表达编码热休克蛋白（DnaJ）和转谷氨酰胺酶基因的大肠杆菌。转谷氨酰胺酶的生产量大、成本低，并具有适当的立体结构，使转谷氨酰胺酶具有生物活性。生产出的转谷氨酰胺酶可用于食品工业。
• Topical composition containing specific flavanones
  申请人：UNILEVER PLC

  公开号：EP0774249A2

  公开（公告）日：1997-05-21

  Cosmetic compositions containing combinations of flavanones:eriodictyol and/or taxifolin combined with taxifolin and/or hesperetin. Alternatively, a flavanone is combined with a short-chain lipid. The compositions enhance keratinocyte differentiation in skin, thus decreasing skin dryness and decreasing appearance of wrinkles.

  含有黄酮类化合物的化妆品组合：eriodictyol和/或taxifolin与taxifolin和/或hesperetin的组合。或者，黄酮与短链脂结合。这些组合物能促进皮肤角质细胞的分化，从而减轻皮肤干燥，减少皱纹的出现。
• COMPOSITION FOR LOCAL ANESTHESIA
  申请人：Showa Yakuhin Kako Co. Ltd

  公开号：EP0858803A1

  公开（公告）日：1998-08-19

  A composition for local anesthesia which comprises (A) lidocaine, (B) a catecholamine such as epinephrine in an amount of, for example, 1/200,000 (g/ml) based on the volume of the composition, and (C) one or more amino acids such as glycine, glutamic acid, and L-glutamic acid-L-lysine or one or more hydroxycarboxylic acids such as lactic acid, glycolic acid, and citric acid, which has a duration suitable for short-time dental operations such as tooth extraction and excellent storage stability.

  一种用于局部麻醉的组合物，它包括(A)利多卡因，(B)儿茶酚胺，如肾上腺素，其用量以组合物体积为基准，例如为1/200,000(克/毫升)，以及(C)一种或多种氨基酸，如甘氨酸、谷氨酸、L-谷氨酸-L-赖氨酸或一种或多种羟基羧酸，如乳酸、乙醇酸和柠檬酸、(C) 一种或多种氨基酸，如甘氨酸、谷氨酸和 L-谷氨酸-L-赖氨酸，或一种或多种羟基羧酸，如乳酸、乙醇酸和柠檬酸。