5-((triisopropylsilyl)ethynyl)isophthalic acid | 1256375-35-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-((triisopropylsilyl)ethynyl)isophthalic acid
• 英文别名: 5-[2-Tri(propan-2-yl)silylethynyl]benzene-1,3-dicarboxylic acid；5-[2-tri(propan-2-yl)silylethynyl]benzene-1,3-dicarboxylic acid
• CAS: 1256375-35-5
• 化学式: C₁₉H₂₆O₄Si
• 分子量: 346.499
• InChiKey: YFHMDAPWKBMDDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.65
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  5-((triisopropylsilyl)ethynyl)isophthalic acid 、 copper(II) nitrate trihydrate 在 2,6-lutidine 作用下， 以 not given 为溶剂， 生成 copper(II) 5-((triisopropylsilyl)ethynyl)isophthalate
  参考文献：
  名称：

  多孔配位纳米笼中的热敏门控效应和选择性气体吸附。

  摘要：

  用24个三异丙基甲硅烷基官能化的多孔配位纳米笼显示出显着的热敏门打开现象，并在一定温度范围内显示出分子筛分效果，可用于气体分离。

  DOI：

  10.1039/c0cc02771e
• 作为产物：
  描述：

  diethyl 5-((triisopropylsilyl)ethynyl)isophthalic acid 在 水 、 potassium hydroxide 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 12.0h， 以1.22 g的产率得到5-((triisopropylsilyl)ethynyl)isophthalic acid
  参考文献：
  名称：

  Interconversion between Discrete and a Chain of Nanocages: Self-Assembly via a Solvent-Driven, Dimension-Augmentation Strategy

  摘要：

  Using a ligand bearing a bulky hydrophobic group, a "shish kabob" of nanocages, has been assembled through either a one-fell-swoop or a step-by-step procedure by varying the dielectric constant of the assembly mixture. A hydrophobic solvent breaks down the chain to discrete nanocages, while a hydrophilic solvent reverses the procedure. Although the shish kabob of nanocages has exactly the same chemical composition and even the same Archimedean-solid structure as those of its discrete analogue, its gas-adsorption capacity is remarkably improved because assembly of a chain exposes the internal surface of an individual cage. This dimension-augmentation strategy may have general implications in the preparation of porous materials.

  DOI：

  10.1021/ja306150x

文献信息

• Two alkynyl functionalized Co(II)-MOFs as fluorescent sensors exhibiting selectivity and sensitivity for Fe3+ and nitroaromatic compounds
  作者：Yue Li、Xia Wang、Chengyong Xing、Xiurong Zhang、Zelong Liang、Xiaokang Wang、Kai Zhang、Yutong Wang、Di Liu、Weidong Fan、Fangna Dai

  DOI：10.1016/j.cclet.2019.03.014

  日期：2019.7

  ([Co(TEPA)(TPT)2/3]·2DMF·H2O) and 2 ([Co(EPA)(TPT)]·1.5DMF·1.5H2O) show excellent luminescence properties. Meanwhile, as fluorescent sensors, complexes 1 and 2 exhibit selectivity and sensitivity for Fe3+ with the Ksv of 1.520 × 104 L/mol and 3.543 × 104 L/mol, which can rapidly detect nitroaromatic compounds in methanol and ethanol, especially for 2,4-NPH through fluorescence quenching with high quenching efficiency

  摘要在设计两个含有炔基官能团的配体的前提下，成功合成了两种结构不同的Co（II）-MOF。配合物1（[Co（TEPA）（TPT）2/3]·2DMF·H2O）和2（[Co（EPA）（TPT）]·1.5DMF·1.5H2O）显示出优异的发光性能。同时，作为荧光传感器，配合物1和2对Fe3 +表现出选择性和敏感性，Ksv为1.520×104 L / mol和3.543×104 L / mol，可以快速检测甲醇和乙醇中的硝基芳香族化合物，尤其是对2,4 -NPH通过荧光猝灭具有很高的猝灭效率。特别是，配合物1和2相对于2,4-NPH的Ksv值可以达到1.627×105 L / mol和9.600×104 L / mol，这表明配合物1和2是识别和检测二甲双胍的良好候选者。 Fe3 +和硝基芳香族化合物。
• (Bio)Functionalisation of Metal–Organic Polyhedra by Using Click Chemistry
  作者：Laura Hernández‐López、Cornelia von Baeckmann、Jordi Martínez‐Esaín、Alba Cortés‐Martínez、Jordi Faraudo、Caterina Caules、Teodor Parella、Daniel Maspoch、Arnau Carné‐Sánchez

  DOI：10.1002/chem.202301945

  日期：2023.10.26

  Copper(I)-catalysed alkyne-azide cycloaddition click chemistry is a versatile post-synthetic tool to functionalize the surface chemistry of alkyne-functionalized cuboctahedral Metal–Organic Polyhedra (MOPs). This methodology enables quantitative functionalization of MOPs with a wide range of functional groups, including polymers, carboxylic and phosphonic acids and biomolecules.

  铜 (I) 催化的炔烃叠氮化物环加成点击化学是一种多功能的合成后工具，可对炔烃功能化的立方八面体金属有机多面体 (MOP) 的表面化学进行功能化。该方法能够对具有多种官能团的 MOP 进行定量官能化，包括聚合物、羧酸和膦酸以及生物分子。
• Interconversion between Discrete and a Chain of Nanocages: Self-Assembly via a Solvent-Driven, Dimension-Augmentation Strategy
  作者：Tian-Fu Liu、Ying-Pin Chen、Andrey A. Yakovenko、Hong-Cai Zhou

  DOI：10.1021/ja306150x

  日期：2012.10.24

  Using a ligand bearing a bulky hydrophobic group, a "shish kabob" of nanocages, has been assembled through either a one-fell-swoop or a step-by-step procedure by varying the dielectric constant of the assembly mixture. A hydrophobic solvent breaks down the chain to discrete nanocages, while a hydrophilic solvent reverses the procedure. Although the shish kabob of nanocages has exactly the same chemical composition and even the same Archimedean-solid structure as those of its discrete analogue, its gas-adsorption capacity is remarkably improved because assembly of a chain exposes the internal surface of an individual cage. This dimension-augmentation strategy may have general implications in the preparation of porous materials.
• Thermosensitive gating effect and selective gas adsorption in a porous coordination nanocage
  作者：Dan Zhao、Daqiang Yuan、Rajamani Krishna、Jasper M. van Baten、Hong-Cai Zhou

  DOI：10.1039/c0cc02771e

  日期：——

  A porous coordination nanocage functionalized with 24 triisopropylsilyl groups exhibits a remarkable thermosensitive gate opening phenomenon and demonstrates a molecular sieving effect at a certain temperature range, which can be used for gas separation purposes.

  用24个三异丙基甲硅烷基官能化的多孔配位纳米笼显示出显着的热敏门打开现象，并在一定温度范围内显示出分子筛分效果，可用于气体分离。