morpholylamide of N(R)-l-ephedrinylacetic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: morpholylamide of N(R)-l-ephedrinylacetic acid
• 英文别名: 2-[(1-Hydroxy-1-phenylpropan-2-yl)-methylamino]-1-morpholin-4-ylethanone
• 化学式: C₁₆H₂₄N₂O₃
• 分子量: 292.378
• InChiKey: CGLMVMMFOQVREH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  53
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  吗啉 、 (5S,6R)-4,5-dimethyl-6-phenyl-2-morpholone 以 异丙醇 为溶剂， 反应 10.0h， 以74.2%的产率得到morpholylamide of N(R)-l-ephedrinylacetic acid
  参考文献：
  名称：

  Synthesis and crystalline and molecular structures of the morpholinylamide of N(R)-l-ephedrinylacetic acid

  摘要：

  The synthesis of the morpholinylamide of N(R)-1-ephedrinylacetic acid has been achieved by the interaction of (5S,6R)-4,5-dimethyl-6-phenylmorpholin-2-one with morpholine, and its structure has been shown by IR and PMR spectroscopies and x-ray structural analysis.

  DOI：

  10.1007/bf02238218

文献信息

• Synthesis and crystalline and molecular structures of the morpholinylamide of N(R)-l-ephedrinylacetic acid
  作者：K. M. Turdybekov、A. B. Shalbaeva、O. A. Nurkenov、A. V. Kanakhin、I. V. Kulakov、A. M. Gazaliev

  DOI：10.1007/bf02238218

  日期：1999.1

  The synthesis of the morpholinylamide of N(R)-1-ephedrinylacetic acid has been achieved by the interaction of (5S,6R)-4,5-dimethyl-6-phenylmorpholin-2-one with morpholine, and its structure has been shown by IR and PMR spectroscopies and x-ray structural analysis.