2-azaniumyl-5-[(5-hydroxy-4,6-dimethylpyrimidin-2-yl)amino]pentanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-azaniumyl-5-[(5-hydroxy-4,6-dimethylpyrimidin-2-yl)amino]pentanoate
• 化学式: C11H18N4O3
• 分子量: 254.29
• InChiKey: DCPBQSFZQHFSMR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  126
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• ADVANCED GLYCATION END PRODUCTS AS ACTIVE INGREDIENTS
  申请人：Huchel Ursula

  公开号：US20100204176A1

  公开（公告）日：2010-08-12

  Cosmetic composition comprising at least one compound from advanced glycation end products (‘AGEs’) and/or precursors thereof as an agent for skin treatment, especially for protection and/or care of the skin. The present invention further provides a cosmetic composition comprising at least one compound from the group of the AGEs and/or precursors thereof, wherein the AGEs are prepared by reacting sugars with the amino acids lysine and/or arginine.
• METHOD FOR THE DETECTION OF PREDIABETES
  申请人：Watanabe Toshiaki

  公开号：US20130004972A1

  公开（公告）日：2013-01-03

  Provided is a method for prediabetes screening by means of methylglyoxal-modified arginine derivative assay, with which it is possible to treat many samples as simply and as safely as with blood sugar assay, and to collect a blood sample taken during a primary health screening in one procedure without imposing any time restraints, complications or risks on the subject. The method for prediabetes screening by means of methylglyoxal-modified arginine derivative assay comprises assaying the methylglyoxal-modified arginine derivative in blood using an assay system which employs an antibody that specifically recognizes methylglyoxal-modified arginine derivative.
• Personal Care Products Containing Extracts of Rosemary
  申请人：Kemin Industries, Inc.

  公开号：US20150164967A1

  公开（公告）日：2015-06-18

  A method of reducing skin damage and/or providing health or cosmetic benefits in a subject, comprising application of a composition containing an effective amount of extracts of rosemary to the skin of the subject.
• BIOMARKERS OF METHYLGLYOXAL AND RELATED METHODS THEREOF
  申请人：THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

  公开号：US20190137505A1

  公开（公告）日：2019-05-09

  The present invention relates to methods and biomarkers for detection, characterization and treatment of conditions associated with methylglyoxal (MG) in biological samples. In particular, the present invention provides compositions and methods for determining diabetic complication onset in a patient through detecting a o-phenylenediamine derivatized MG (2MQ) product as indicative of the presence of MG, impaired fibrinolysis in a patient through detecting a MG modified plasminogen (Pg) product as indicative of impaired fibrinolysis, and the efficacy of metformin (MF) treatment in a patient through detecting IMZ as indicative of a MF/MG product.
• US8202892B2
  申请人：——

  公开号：US8202892B2

  公开（公告）日：2012-06-19