1,2-diacetoxy-3-methoxypropane | 15803-58-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 1,2-diacetoxy-3-methoxypropane
• 英文别名: 1,2-diacetoxy-3-methoxy-propane；1,2-Diacetoxy-3-methoxy-propan；2-(Acetyloxy)-1-(methoxymethyl)ethyl acetate；(2-acetyloxy-3-methoxypropyl) acetate
• CAS: 15803-58-4
• 化学式: C₈H₁₄O₅
• 分子量: 190.196
• InChiKey: DHGBJGAVVUYAID-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  61.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1,2-diacetoxy-3-methoxypropane 生成 (S)-1,2-diacetoxy-3-methoxypropane
  参考文献：
  名称：

  Lipase-catalyzed enantiomer selective hydrolysis of 1,2-diol diacetates

  摘要：

  Enantiomer selective hydrolysis of racemic 1,2-diol diacetates (rac-2a-h) was investigated by using the inexpensive commercial porcine pancreatic lipase. The hydrolysis proceeds with variable regioselectivity but with moderate to good enantioselectively yielding a mixture of isomeric monoacetates (3a-h and 4a-h) and unchanged diacetate enantiomers (2a-h). Evidence was found that both monoacetates (3a-h and 4a-h) are formed with the same sense of enantiomer selectivity.

  DOI：

  10.1016/s0957-4166(00)80071-3
• 作为产物：
  描述：

  3-甲氧基-1,2-丙二醇 、 乙酸酐 在 硫酸 作用下， 反应 0.25h， 以88%的产率得到1,2-diacetoxy-3-methoxypropane
  参考文献：
  名称：

  Lipase-catalyzed enantiomer selective hydrolysis of 1,2-diol diacetates

  摘要：

  Enantiomer selective hydrolysis of racemic 1,2-diol diacetates (rac-2a-h) was investigated by using the inexpensive commercial porcine pancreatic lipase. The hydrolysis proceeds with variable regioselectivity but with moderate to good enantioselectively yielding a mixture of isomeric monoacetates (3a-h and 4a-h) and unchanged diacetate enantiomers (2a-h). Evidence was found that both monoacetates (3a-h and 4a-h) are formed with the same sense of enantiomer selectivity.

  DOI：

  10.1016/s0957-4166(00)80071-3

文献信息

• Leather treatment
  申请人：Slattery Doug

  公开号：US20060042018A1

  公开（公告）日：2006-03-02

  An improved method for dying leather with propylene glycol monomethyl ether (PGME) systems comprising adding polyacrylate resin base, C3 and C4 alcohols, and n-butyl acetate and negating the need for teflon dispersions, dibutyl phthalate, and improves the dye penetration, hastens the flash times, improve the dust free time, and improves the tape time.

  一种使用丙二醇单甲醚（PGME）系统对皮革进行染色的改进方法，包括添加聚丙烯酸酯树脂基、C3 和 C4 醇以及醋酸正丁酯，无需使用聚四氟乙烯分散体和邻苯二甲酸二丁酯，并能提高染料渗透性、加快闪蒸时间、改善无尘时间和改善胶带时间。
• Fairbourne; Gibson; Stephens, Chemistry and industry, 1930, p. 1022
  作者：Fairbourne、Gibson、Stephens

  DOI：——

  日期：——
• Comb (block) copolymers
  申请人：Göbelt Bernd

  公开号：US20100099813A1

  公开（公告）日：2010-04-22

  The present invention relates to comb (block) copolymers obtainable by reacting I at least one (block) copolymer comprising polymerised, optionally substituted styrene and maleic anhydride units, which copolymer has been obtained by living, free-radical polymerisation, with II at least one polyalkylene oxide monoamine comprising a primary amino end group at a reaction temperature of ≧150° C. and by subsequent salification of at least 25 mol % of the free carboxyl groups of the reaction product at a reaction temperature of <100° C. and optionally after addition of H 2 O and to the use of these comb copolymers as wetting agents and dispersants.
• POLYMER FILM, AND OPTICALLY-COMPENSATORY FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE COMPRISING THE SAME
  申请人：Nishiura Takako

  公开号：US20130253182A1

  公开（公告）日：2013-09-26

  A polymer film that has an in-plane retardation Re (λ) and a thickness-direction retardation Rth (λ) satisfying formula (i) and (ii), and that further has a surface energy of at least one surface is from 50 mN/m to 80 mN/m: 0≦ Re (630) ≦10, and | Rth (630) |≦25;  (i) and | Re (400) −Re (700) |≦10, and | Rth (400) −Rth (700) |≦35.  (ii) in the formulae, Re (λ) and Rth (λ) are measurement values at the wavelength of λ nm, and an optically-compensatory film, an optical material such as a polarizer and a liquid-crystal display device using the polymer film.
• SODIUM CHANNEL BLOCKERS FOR SKIN DISORDERS
  申请人：PARION SCIENCES, INC.

  公开号：US20180092915A1

  公开（公告）日：2018-04-05

  Provided are methods of treating a variety of disorders of the skin with inhibitors of the epithelial sodium channel (ENaC). The inhibitors are represented by formula (I)-(IV): where R is defined herein.