C4-HSL | 912545-51-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: C4-HSL
• 英文别名: 3-hydroxy-butanoyl homoserine lactone；3-hydroxy-N-(2-oxooxolan-3-yl)butanamide
• CAS: 912545-51-8
• 化学式: C₈H₁₃NO₄
• 分子量: 187.196
• InChiKey: FIXDIFPJOFIIEC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  75.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Methods For The Treatment Of An Infectious Bacterial Disease With An Anti-Lactone Or Lactone Derived Signal Molecules Antibody
  申请人：Charlton Keith Alan

  公开号：US20100303831A1

  公开（公告）日：2010-12-02

  The present invention relates to methods for the control of virulence of infectious bacteria by modulating the extra-cellular concentration of bacterial cell signalling molecules. Derivatives of cell signalling molecules are conjugated to suitable carrier proteins and used to isolate high affinity receptors recognising the native signal molecule(s). By binding to signalling molecules, the receptors reduce and maintain extra-cellular concentrations of signal molecules below the threshold level that would otherwise result in certain opportunistic pathogens adopting a virulent form, and can transform virulent organisms to non-virulent states. These receptors have applications for the treatment of individuals with susceptibility to infection, the treatment of patients with existing infections, in disease monitoring and management, and in related applications where the host for infection is an animal or plant.
• ACYL-HOMOSERINE LACTONE DERIVATIVES FOR IMPROVING PLANT YIELD
  申请人：Dahmen Peter

  公开号：US20140221210A1

  公开（公告）日：2014-08-07

  The present invention relates to methods for improving crop yield, chlorophyll content, seed germination, nutrient uptake or mycorrhizal symbiotic interaction of a plant, comprising the use of acyl-homoserine lactone derivatives and to composition comprising said derivatives of formula (I) or (II) wherein R1 is hydrogen or hydroxyl; R2 is a saturated or mono-unsaturated linear aliphatic group comprising 1 to 15 atoms.
• US7812134B2
  申请人：——

  公开号：US7812134B2

  公开（公告）日：2010-10-12
• US8168397B2
  申请人：——

  公开号：US8168397B2

  公开（公告）日：2012-05-01