Lysylisoleucine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Lysylisoleucine
• 英文别名: 2-(2,6-diaminohexanoylamino)-3-methylpentanoic acid
• 化学式: C₁₂H₂₅N₃O₃
• 分子量: 259.35
• InChiKey: FMIIKPHLJKUXGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.2
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  118
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• CULTURE MEDIUM COMPRISING OLGOPEPTIDES
  申请人：Evonik Technochemie GmbH

  公开号：EP3372671A1

  公开（公告）日：2018-09-12

  The invention relates to a culture medium, preferably a cell culture medium, comprising an oligopeptide of 2-10 amino acid units in length, said amino acid units being natural amino acids, and at least one amino acid unit being a lysine unit, the oligopeptide not comprising glycine (Gly) and glutamic acid (Glu) and the tripeptide Lys-Lys-Lys being excluded. The invention further relates to the use of a culture medium of the invention for culturing cells, preferably plant cells, animal cells or mammalian cells. Another aspect of the invention relates to a method of manufacturing a cell culture product comprising the steps of (i) providing a cell capable of producing said cell culture product; (ii) contacting said cell with a culture medium according to the invention; and (iii) obtaining said cell culture product from said culture medium or from said cell.

  本发明涉及一种培养基，最好是细胞培养基，包含长度为 2-10 个氨基酸单位的寡肽，所述氨基酸单位为天然氨基酸，至少一个氨基酸单位为赖氨酸单位，寡肽不包括甘氨酸（Gly）和谷氨酸（Glu），也不包括三肽 Lys-Lys-Lys。 本发明还涉及使用本发明的培养基培养细胞，最好是植物细胞、动物细胞或哺乳动物细胞。 本发明的另一个方面涉及一种制造细胞培养产品的方法，包括以下步骤：(i) 提供能够生产所述细胞培养产品的细胞；(ii) 将所述细胞与根据本发明的培养基接触；(iii) 从所述培养基或所述细胞中获得所述细胞培养产品。
• METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION
  申请人：The Board of Regents of The University of Texas System

  公开号：EP2776829A1

  公开（公告）日：2014-09-17
• [EN] METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION<br/>[FR] PROCÉDÉS ET UTILISATIONS DE PROFILAGE MÉTABOLIQUE POUR UNE INFECTION PAR CLOSTRIDIUM DIFFICILE (CDI)
  申请人：UNIV TEXAS

  公开号：WO2013070962A1

  公开（公告）日：2013-05-16

  Embodiments include methods for generating a metabolite profile of a stool sample and methods of assessing the status of a subject using the metabolic profile derived from a stool sample.
• [EN] CULTURE MEDIUM COMPRISING OLIGOPEPTIDES<br/>[FR] MILIEU DE CULTURE COMPRENANT DES OLIGOPEPTIDES
  申请人：EVONIK TECHNOCHEMIE GMBH

  公开号：WO2018162346A1

  公开（公告）日：2018-09-13

  The invention relates to a culture medium, preferably a cell culture medium, comprising at least one oligopeptide of 2-10 amino acids in length, said amino acids being natural amino acids and at least one of said amino acids being lysine (Lys) and one further amino acid is selected from cysteine (Cys), cystine (Cyss), leucine (Leu), tyrosine (Tyr), valine (Val) and Isoleucine (Ile) and the oligopeptide is present in an amount of at least 0.1 mM. The invention further relates to the use of a culture medium of the invention for culturing cells, preferably plant cells, animal cells or mammalian cells. Another aspect of the invention relates to a method of manufacturing a cell culture product comprising the steps of (i) providing a cell capable of producing said cell culture product; (ii) contacting said cell with a culture medium according to the invention; and (iii) obtaining said cell culture product from said culture medium or from said cell.