[3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] hexadecanoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: [3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] hexadecanoate
• 化学式: C₂₂H₄₂O₇
• 分子量: 418.6
• InChiKey: FPAQFGDNJSALCJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  29
• 可旋转键数：
  17
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  116
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES
  申请人：The University of Texas M.D. Anderson Cancer

  公开号：EP2663314A2

  公开（公告）日：2013-11-20
• [EN] MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES<br/>[FR] COMPOSÉS À BASE DE MONOSACCHARIDES POUR LE TRAITEMENT DE MALADIES DERMATOLOGIQUES PROLIFÉRATIVES ET INFLAMMATOIRES
  申请人：INTERTECH BIO LLC

  公开号：WO2012097052A2

  公开（公告）日：2012-07-19

  The present invention relates to compounds and methods which may be useful as inhibitors of glycolysis, inhibitors of protein glycosylation, anti-virals, and down-regulators of insulin receptor and IGF- 1 receptor for the treatment or prevention of inflammatory dermatological diseases or proliferative dermatological diseases.
• [EN] METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF<br/>[FR] PROCÉDÉ DE TRAITEMENT D'INFECTIONS VIRALES AVEC DES MONOSACCHARIDES DE TYPE HEXOSES ET LEURS ANALOGUES
  申请人：UNIV TEXAS

  公开号：WO2021188586A1

  公开（公告）日：2021-09-23

  The present invention relates to methods of treating and preventing viral diseases and infections comprising the administration of hexoses and analogs and their prodrugs thereof that inhibit glycolysis and/or glycosylation.