4-Hydroxy-6-(4-methyl-2-oxopentyl)-2H-pyran-2-one | 327175-06-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃
• 英文名称: 4-Hydroxy-6-(4-methyl-2-oxopentyl)-2H-pyran-2-one
• 英文别名: 4-hydroxy-6-(4-methyl-2-oxopentyl)pyran-2-one
• CAS: 327175-06-4
• 化学式: C₁₁H₁₄O₄
• 分子量: 210.23
• InChiKey: GACVANPZCDHOHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• MICROORGANISM PRODUCTION OF HIGH-VALVE CHEMICAL PRODUCTS, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
  申请人：OPX Biotechnologies Inc.

  公开号：EP2529023A1

  公开（公告）日：2012-12-05
• MICROBIAL PRODUCTION OF CHEMICAL PRODUCTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
  申请人：OPX Biotechnologies Inc.

  公开号：EP2689020A1

  公开（公告）日：2014-01-29
• MICROORGANISM PRODUCTION OF HIGH-VALUE CHEMICAL PRODUCTS, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
  申请人：OPX Biotechnologies, Inc.

  公开号：US20150056651A1

  公开（公告）日：2015-02-26

  This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a chemical product, which includes polyketides and 3-hydroxypropionic acid.
• [EN] MICROORGANISM PRODUCTION OF HIGH-VALVE CHEMICAL PRODUCTS, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS<br/>[FR] PRODUCTION PAR MICRO-ORGANISMES DE PRODUITS CHIMIQUES DE GRANDE QUALITÉ, COMPOSITIONS, PROCÉDÉS ET SYSTÈMES ASSOCIÉS
  申请人：OPX BIOTECHNOLOGIES INC

  公开号：WO2011094457A1

  公开（公告）日：2011-08-04

  This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a chemical product, which includes polyketides and 3-hydroxypropionic acid.
• [EN] MICROBIAL PRODUCTION OF CHEMICAL PRODUCTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS<br/>[FR] PRODUCTION MICROBIENNE DE PRODUITS CHIMIQUES, ET COMPOSITIONS, PROCÉDÉS ET SYSTÈMES ASSOCIÉS
  申请人：OPX BIOTECHNOLOGIES INC

  公开号：WO2012129450A1

  公开（公告）日：2012-09-27

  Metabolically engineered microorganism strains are disclosed, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a chemical product. Such chemical products include polyketides, 3-hydroxypropionic acid, and various other chemical products described herein. Methods of production also may be applied to further downstream products, such as consumer products. In various embodiments, modifications to a microorganism and/or culture system divert, at least transiently, usage of malonyl-coA from the fatty acid biosynthesis pathway and thereby provides for usage of the malonyl-coA for a chemical product other than a fatty acid. In various embodiments, the fatty acid biosynthesis pathway is modulated to produce specific fatty acids or combinations of fatty acids.