(2-decenyl)succinic anhydride | 62568-81-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2-decenyl)succinic anhydride
• 英文别名: 3-Dec-2-enyloxolane-2,5-dione
• CAS: 62568-81-4
• 化学式: C₁₄H₂₂O₃
• 分子量: 238.327
• InChiKey: GDXGTHFUAURIFL-UHFFFAOYSA-N

物化性质

• 沸点：
  359.6±11.0 °C(Predicted)
• 密度：
  1.009±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  17
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (2-decenyl)succinic anhydride 、 东莨菪碱 在 4-二甲氨基吡啶 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 8.33h， 生成
  参考文献：
  名称：

  一种用于改善微循环障碍的新化合物及其制 法

  摘要：

  本发明涉及药物化学技术领域，且公开了一种用于改善微循环障碍的新化合物，新化合物化学通式为：该一种用于改善微循环障碍的新化合物，通过不同浓度的新化合物分别处理斑马鱼，相比于正常组和对照组，在不同浓度下，新化合物分别处理的斑马鱼对普纳替尼诱导血栓模型斑马鱼的血流动力学具有明显的改善作用，对花生四烯酸诱导的斑马鱼血栓形成具有显著的预防作用，对普纳替尼诱发的斑马鱼血管内皮损伤均具有良好的保护作用，对LPS诱导的斑马鱼炎症均具有显著的抗炎作用，能明显抑制炎症斑马鱼凝血因子V(f5)的表达，并且新化合物有良好的抗氧化作用，对微循环障碍具有明显的改善和优异的治疗效果。

  公开号：

  CN110698531B

文献信息

• Laundry Care Compositions Containing Dyes
  申请人：Torres Eduardo

  公开号：US20130245242A1

  公开（公告）日：2013-09-19

  This application relates to laundry care compositions comprising thiophene azo carboxylate fabric shading dyes and methods of treating a textile comprising such laundry care compositions.

  本申请涉及包含噻吩偶氮羧酸酯织物着色染料的洗衣护理组合物以及处理包含此类洗衣护理组合物的纺织品的方法。
• Compounds and pharmaceutical preparations having calcium - regulatory activity
  申请人：University of Lancaster

  公开号：EP0240257A2

  公开（公告）日：1987-10-07

  Pharmaceutical compositions useful in regulating calcium transport across cellular membranes in man and ani­mals are disclosed. The compositions contain plant growth regulators such as abscisic acid and its derivatives. In particular, the compositions contain a compound of the for­mula: or R₁ - Y - R₂ wherein R₁ is an alkyl of up to seven carbons or a saturated or unsaturated six membered carbon ring, which may be sub­stituted; R₂ is a cyano group, a thio or hydroxy lower alkyl group or a group containing a carbonyl, most commonly a carboxyl group; R₃ is hydrogen or lower alkyl; R₄ is hydro­gen, lower alkyl or halide; R₅ is hydrogen or hydroxy; R₆ is hydrogen, carboxy or carboxy lower alkyl, or R₅ and R₆ form a bond between the carbons to which they are attached or with the carbons to which they are attached form a carbon ring; or R₂ and R₆ together with the carbon to which they are bonded form a heterocyclic ring; n is 0 or 1, with the proviso that when n is 0, R₂ is an acyl group; X is -CH₂-, -­CH=CH-, -CH₂-CH₂-, -CH₂-NH-, -CH₂-O-, -CH₂-S- or -NH-CO-; and Y is a carbocyclic group bonded to R₁ and R₂ through a single carbon. The compositions are formulated for oral, parenteral or other form of administration in dosages neces­sary to effect the desired change in calcium flux. Daily doses of 0.01 to 200 mg/kg in one or more doses are contem­plated. Dosage units may be formulated with any pharma­ceutically acceptable carrier which is compatible with the active ingredient.

  本发明公开了可用于调节人和动物细胞膜钙转运的药物组合物。这些组合物含有植物生长调节剂，如脱落酸及其衍生物。特别是，组合物中含有一种式的化合物： 或 R₁ - Y - R₂ 其中，R₁ 是最多七个碳原子的烷基或饱和或不饱和的六分子碳环，可以被取代；R₂ 是氰基、硫代或羟基低级烷基或含有羰基的基团，最常见的是羧基；R₃ 是氢或低级烷基；R₄ 是氢、低级烷基或卤化物；R₅ 是氢或羟基；R₆ 是氢、羧基或羧基低级烷基，或 R₅ 和 R₆ 在所连接的碳之间形成键，或与所连接的碳一起形成碳环；或 R₂ 和 R₆ 与所连接的碳一起形成杂环；n 为 0 或 1，但当 n 为 0 时，R₂ 为酰基；X 为-CH₂-、-CH=CH-、-CH₂-CH₂-、-CH₂-NH-、-CH₂-O-、-CH₂-S-或-NH-CO-；Y 是通过一个碳与 R₁ 和 R₂ 键合的碳环基团。组合物配制成口服、肠外或其他形式的给药剂量，以实现所需的钙通量变化。日剂量为 0.01 至 200 毫克/千克，可考虑一次或多次给药。剂量单位可与任何与活性成分相容的药学上可接受的载体配制。
• Condensation polymers containing dialkylamide endgroups, process for their production and applications thereof
  申请人：DSM N.V.

  公开号：EP1038902A1

  公开（公告）日：2000-09-27

  The invention relates to a condensation polymer, as well as to a process for preparation said polymers, having at least one dialkylamide endgroup connected through the polymer backbone to a unit derived from an alkylamide, the connection comprising at least one ester linkage. The polymer according to the invention can be linear or branched. The condensation polymers can be very widely used in technically different fields, both in thermosetting and in thermoplastic applications. The invention also relates to a composition comprising the condensation polymer according to the invention, an active substance and a polymer, as well as to a process for incorporating an active substance in an object comprising at least of a polymer composition, by bringing the object into contact with the active substance. More in particular, the invention relates to the dying of polymer fibres.

  本发明涉及一种缩合聚合物以及制备上述聚合物的工艺，该聚合物至少有一个二烷基酰胺端基，通过聚合物骨架与烷基酰胺衍生的单元连接，该连接至少包括一个酯连接。根据本发明，聚合物可以是线性的，也可以是支链的。缩聚聚合物可广泛应用于不同的技术领域，包括热固性和热塑性应用。本发明还涉及一种由本发明的缩聚聚合物、活性物质和聚合物组成的组合物，以及一种通过使物体与活性物质接触，将活性物质加入至少由聚合物组合物组成的物体中的工艺。更具体地说，本发明涉及聚合物纤维的染色。
• Condensation polymer containing dialkylamide endgroups, process for producing said condensation polymers and applications thereof
  申请人：DSM N.V.

  公开号：US20020019509A1

  公开（公告）日：2002-02-14

  The invention relates to a condensation polymer, as well as to a process for preparation said polymers, having at least one dialkylamide endgroup connected through the polymer backbone to a unit derived from an alkylamide, the connection comprising at least one ester linkage. The polymer according to the invention can be linear or branched. The condensation polymers can be very widely used in technically different fields, both in thermosetting and in thermoplastic applications. The invention also relates to a composition comprising the condensation polymer according to the invention, an active substance and a polymer, as well as to a process for incorporating an active substance in an object comprising at least of a polymer composition, by bringing the object into contact with the active substance. More in particular, the invention relates to the dying of polymer fibers.

  本发明涉及一种缩合聚合物以及制备上述聚合物的工艺，该聚合物至少有一个二烷基酰胺端基，通过聚合物骨架与烷基酰胺衍生的单元连接，该连接至少包括一个酯连接。根据本发明，聚合物可以是线性的，也可以是支链的。缩聚聚合物可广泛应用于不同的技术领域，包括热固性和热塑性应用。本发明还涉及一种由本发明的缩聚聚合物、活性物质和聚合物组成的组合物，以及一种通过使物体与活性物质接触，将活性物质加入至少由聚合物组合物组成的物体中的工艺。更具体地说，本发明涉及聚合物纤维的染色。
• On-spot hydrophilic enhanced slide and preparation thereof
  申请人：——

  公开号：US20020122875A1

  公开（公告）日：2002-09-05

  The invention discloses an on-spot hydrophilic enhanced slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing functional groups such as anhydride, imide, cyclic amide, and cyclic ester, and application of the hydrophobic copolymer onto an organic or inorganic substrate. The resulting slide has the properties of on-spot hydrophilic/hydrophobic dynamic conversion, as well as on-spot hydrophilic enhancement for the preparation of high-density and high-efficiency bio-chip/microarray.

  本发明公开了一种现场亲水增强载玻片/微阵列。该制备方法涉及一种疏水共聚物，其制备方法是将疏水材料与带有酸酐、亚胺、环酰胺和环酯等官能团的化合物混合、接枝或共聚，然后将疏水共聚物涂覆在有机或无机基底上。所制得的载玻片具有现场亲水/疏水动态转换的特性，以及现场亲水增强的特性，可用于制备高密度、高效率的生物芯片/微阵列。