1-(1-Dodecoxy-3,3-diethoxypropyl)benzotriazole | 186762-59-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并三唑类
• 英文名称: 1-(1-Dodecoxy-3,3-diethoxypropyl)benzotriazole
• CAS: 186762-59-4
• 化学式: C₂₅H₄₃N₃O₃
• 分子量: 433.635
• InChiKey: PYVFFBFMLAMARI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  31
• 可旋转键数：
  19
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.76
• 拓扑面积：
  58.4
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  苯基溴化镁 、 1-(1-Dodecoxy-3,3-diethoxypropyl)benzotriazole 以 乙醚 、 甲苯 为溶剂， 反应 1.0h， 以29%的产率得到(1-Dodecyloxy-3,3-diethoxy-propyl)-benzene
  参考文献：
  名称：

  Lewis Acid-Catalyzed Additions of (Benzotriazol-1-yl)diethoxymethane to Enol Ethers and Enamides. New Syntheses of β-Alkoxyalkanal and β-Aminoalkanal Acetals

  摘要：

  Addition of (benzotriazol-1-yl)diethoxymethane 11 to various acyclic and cyclic enol ethers and enamides produces the corresponding adducts, which were reacted with either NaAlH4 or Grignard reagents to afford acyclic acetal-ethers (18a-f), cyclic alpha-(substituted)-beta-acetals (19a-c), amino-acetals (24a,b), and 1,3-amino-ethers (25), all known but previously difficult-to-access classes of compounds.

  DOI：

  10.1021/jo9612335
• 作为产物：
  描述：

  T406石油添加剂 在 对甲苯磺酸 作用下， 以 various solvent(s) 为溶剂， 反应 22.0h， 生成 1-(1-Dodecoxy-3,3-diethoxypropyl)benzotriazole
  参考文献：
  名称：

  Lewis Acid-Catalyzed Additions of (Benzotriazol-1-yl)diethoxymethane to Enol Ethers and Enamides. New Syntheses of β-Alkoxyalkanal and β-Aminoalkanal Acetals

  摘要：

  Addition of (benzotriazol-1-yl)diethoxymethane 11 to various acyclic and cyclic enol ethers and enamides produces the corresponding adducts, which were reacted with either NaAlH4 or Grignard reagents to afford acyclic acetal-ethers (18a-f), cyclic alpha-(substituted)-beta-acetals (19a-c), amino-acetals (24a,b), and 1,3-amino-ethers (25), all known but previously difficult-to-access classes of compounds.

  DOI：

  10.1021/jo9612335

文献信息

• Lewis Acid-Catalyzed Additions of (Benzotriazol-1-yl)diethoxymethane to Enol Ethers and Enamides. New Syntheses of β-Alkoxyalkanal and β-Aminoalkanal Acetals
  作者：Alan R. Katritzky、Sergei A. Belyakov、Bogumila Rachwal、Jean-Luc Moutou

  DOI：10.1021/jo9612335

  日期：1997.2.1

  Addition of (benzotriazol-1-yl)diethoxymethane 11 to various acyclic and cyclic enol ethers and enamides produces the corresponding adducts, which were reacted with either NaAlH4 or Grignard reagents to afford acyclic acetal-ethers (18a-f), cyclic alpha-(substituted)-beta-acetals (19a-c), amino-acetals (24a,b), and 1,3-amino-ethers (25), all known but previously difficult-to-access classes of compounds.