17-Hydroxy-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoctadecanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 17-Hydroxy-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoctadecanoic acid
• 英文别名: 17-hydroxy-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoctadecanoic acid
• 化学式: C₂₄H₄₆O₈
• 分子量: 462.6
• InChiKey: HBVOFRPVBQZAOZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  32
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  137
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• NOVEL RHAMNOLIPID COMPOUNDS AND USE THEREOF
  申请人：KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY

  公开号：US20210355151A1

  公开（公告）日：2021-11-18

  Disclosed are a novel rhamnolipid compound, an optical isomer thereof, or a pharmaceutically acceptable salt thereof in the present disclosure. The novel rhamnolipid compound, the optical isomer thereof, or the pharmaceutically acceptable salt thereof selectively exhibits cytotoxicity to human cancer cell lines, thereby inhibiting the growth of cancer cells, and thus has particularly excellent preventive or therapeutic effects against the above-mentioned types of cancers.
• [EN] NOVEL RHAMNOLIPID COMPOUND AND USE THEREOF<br/>[FR] NOUVEAU COMPOSÉ RHAMNOLIPIDE ET SON UTILISATION<br/>[KO] 신규 람노리피드 화합물 및 이의 용도
  申请人：KOREA INST OCEAN SCI & TECH

  公开号：WO2020158995A1

  公开（公告）日：2020-08-06

  본 발명은, 신규 람노리피드 화합물, 이의 광학이성질체 또는 이의 약학적으로 허용가능한 염을 제공한다. 본 발명에 따른 신규 람노리피드 화합물, 이의 광학이성질체 또는 이의 약학적으로 허용가능한 염은 인간 암 세포주에 대한 세포 독성을 나타내어 암 세포의 성장을 억제함으로써, 특히 위 언급된 암에 대하여 우수한 예방 또는 치료 효과를 가진다.