fesumtuorin C

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: fesumtuorin C
• 英文别名: 9-[3-Hydroxy-2-[3-hydroxy-2-methyl-4-(7-oxofuro[3,2-g]chromen-4-yl)oxybutan-2-yl]oxy-3-methylbutoxy]furo[3,2-g]chromen-7-one
• 化学式: C₃₂H₃₀O₁₁
• 分子量: 590.584
• InChiKey: IIVLKXAGPYYIDA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  43
• 可旋转键数：
  10
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  147
• 氢给体数：
  2
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 fesumtuorin C 在 吡啶 作用下， 生成 Acetic acid 2-[2-hydroxy-2-methyl-1-(7-oxo-7H-furo[3,2-g]chromen-9-yloxymethyl)-propoxy]-2-methyl-1-(7-oxo-7H-furo[3,2-g]chromen-4-yloxymethyl)-propyl ester
  参考文献：
  名称：

  Coumarins and bicoumarin from Ferula sumbul: anti-HIV activity and inhibition of cytokine release

  摘要：

  The methanol extract of the dried roots of Ferula sumbul afforded two furanocoumarin esters, fesumtuorin A, B, one bicoumarin, fesumtuorin C, five spirobicoumarins, fesumtuorin D, E, F, G and H, along with nineteen known coumarins. Their structures were established on the basis of spectroscopic studies. Some of the isolated compounds showed anti-HIV activity and very weak inhibition of cytokine release. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(99)00554-3