Glycinamide, L-alanyl-L-leucyl- | 325690-84-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Glycinamide, L-alanyl-L-leucyl-
• 英文别名: (2S)-N-(2-amino-2-oxoethyl)-2-[[(2S)-2-aminopropanoyl]amino]-4-methylpentanamide
• CAS: 325690-84-4
• 化学式: C₁₁H₂₂N₄O₃
• 分子量: 258.32
• InChiKey: YFVZZFQMVKXLHX-YUMQZZPRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  127
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• Peptides that block viral infectivity and methods of use thereof
  申请人：——

  公开号：US20020091086A1

  公开（公告）日：2002-07-11

  The discovery of peptides in amide form that inhibit viral infection, including human immunodeficiency virus (HIV) infection is disclosed. Methods of use of peptides are also disclosed including use in medicaments for the treatment and prevention of viral infection, such as HIV infection.

  本发明公开了抑制病毒感染（包括人类免疫缺陷病毒（HIV）感染）的酰胺形式的肽。还公开了肽的使用方法，包括用于治疗和预防病毒感染（如 HIV 感染）的药物。
• Protein polymerization inhibitors and methods of use
  申请人：——

  公开号：US20030050242A1

  公开（公告）日：2003-03-13

  The present invention is related to the discovery of peptides that modulate the protein-protein interactions necessary for protein polymerization and the assembly of supramolecular protein complexes. More specifically, biotechnological tools and medicaments comprising various small peptides that have a modified carboxyl terminus are disclosed for use in the study and treatment or prevention of human disease.

  本发明涉及发现能调节蛋白质聚合和超分子蛋白质复合物组装所需的蛋白质-蛋白质相互作用的肽。更具体地说，本发明公开了由具有修饰羧基末端的各种小肽组成的生物技术工具和药物，用于研究、治疗或预防人类疾病。
• PHARMACEUTICAL COMPOSITIONS CONTAINING TRIPEPTIDES
  申请人：TRIPEP AB

  公开号：EP1207897A2

  公开（公告）日：2002-05-29
• Molecules that block viral infectivity and methods of use thereof
  申请人：Goobar-Larsson Laura

  公开号：US20070037249A1

  公开（公告）日：2007-02-15

  Embodiments relate to the discovery that certain tripeptide amides and glycine amide can be used to inhibit viral infection, including human immunodeficiency virus (HIV) infection. More specifically, medicaments comprising said tripeptide amides and/or glycine amide and methods of using said compounds for the prevention and treatment of viral infection, such as HIV infection, are provided.
• US6258932B1
  申请人：——

  公开号：US6258932B1

  公开（公告）日：2001-07-10