N-palmitoyltyrosine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-palmitoyltyrosine
• 英文别名: N-Palmitoyl-L-tyrosine；2-(hexadecanoylamino)-3-(4-hydroxyphenyl)propanoic acid
• 化学式: C₂₅H₄₁NO₄
• 分子量: 419.605
• InChiKey: IPAZGTSTZYXZAT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  30
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  86.6
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• [EN] N-ACYL-TYROSINE DERIVATIVES AND USES THEREOF<br/>[FR] DÉRIVÉS DE N-ACYLE-TYROSINE ET LEURS UTILISATIONS
  申请人：UNIV OF PRINCE EDWARD ISLAND

  公开号：WO2021046651A1

  公开（公告）日：2021-03-18

  Provided herein are compounds of Formula A, methods for the preparation thereof, and uses thereof for treating or preventing bacterial infections.

  本文提供了A式化合物，其制备方法以及用于治疗或预防细菌感染的用途。
• PHOSPHONATE DERIVATIVES AS AUTOTAXIN INHIBITORS
  申请人：Lynch Kevin R.

  公开号：US20100016258A1

  公开（公告）日：2010-01-21

  The present invention provides β-hydroxy phosphonate compounds that are autotaxin inhibitors.

  本发明提供了一种β-羟基膦酸酯化合物，它们是自动税感受器抑制剂。
• NOVEL COMPOUND ACCELERATING SECRETION OF HUMAN-DERIVED ANTI-MICROBIAL PEPTIDE, METHOD FOR PREPARING SAME, AND COMPOSITION HAVING SAME AS ACTIVE INGREDIENT
  申请人：Neopharm Co., Ltd.

  公开号：US20130190397A1

  公开（公告）日：2013-07-25

  Disclosed is a compound having an acceleration effect on the secretion of human β-defensin, LL-37, which is a human-derived anti-microbial peptide, a method for preparing same, and a composition for accelerating the secretion of anti-microbial peptide having same as an active ingredient, and the compound and the composition using same of the present invention enhance the anti-microbial effect and the immunity control effect that the anti-microbial peptide has in the body by accelerating the secretion of the anti-microbial peptide in the body.

  本发明揭示了一种具有促进人类β-防御素LL-37分泌的加速效果的化合物，该化合物是一种源自人体的抗微生物肽，提供了制备该化合物的方法以及以其为活性成分的促进抗微生物肽分泌的组合物。本发明的化合物和组合物通过加速体内抗微生物肽的分泌，增强了抗微生物肽在人体内具有的抗微生物效果和免疫控制效果。
• Liposome delivery of compositions to enhance tanning and repair UV damage
  申请人：CALIFORNIA SUNCARE INC.

  公开号：EP0707844A2

  公开（公告）日：1996-04-24

  The present invention concerns the delivery in carrier liposomes of novel combinations of two or more active ingredients designed to enhance tanning and ameliorate damage to skin and DNA caused by UV radiation.

  本发明涉及在载体脂质体中输送两种或两种以上活性成分的新型组合，旨在增强美黑效果并改善紫外线辐射对皮肤和 DNA 造成的损伤。
• Cosmetic compositions comprising sclareolide and hesperidin methyl chalcone
  申请人：Cognis IP Management GmbH

  公开号：EP2014276A1

  公开（公告）日：2009-01-14

  The present invention relates to cosmetic compositions comprising sclareolide and hesperidin methyl chalcone (HMC), which can be used especially for the tanning of skin and/or the darkening of hair and/or preventing of greying of hair. The present invention also relates to the use of agents for these purposes.

  本发明涉及包含香紫苏内酯和橙皮甙甲基查尔酮（HMC）的化妆品组合物，该组合物尤其可用于皮肤晒黑和/或头发变黑和/或防止头发变白。本发明还涉及用于上述目的的制剂的使用。