15-Hydroxy-pentacosanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 15-Hydroxy-pentacosanoic acid
• 英文别名: 15-hydroxypentacosanoic acid
• 化学式: C₂₅H₅₀O₃
• 分子量: 398.7
• InChiKey: JIUVLHYELZYWJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.3
• 重原子数：
  28
• 可旋转键数：
  23
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• A PHARMACEUTICAL COMPOSITION FOR THE PREVENTION/TREATMENT OF BONE DISORDERS AND A PROCESS FOR THE PREPARATION THEREOF
  申请人：Council of Scientific and Industrial Research

  公开号：EP1993579A2

  公开（公告）日：2008-11-26
• Pharmaceutical Composition for the Prevention/Treatment of Bone Disorders and a Process for the Preparation Thereof
  申请人：Maurya Rakesh

  公开号：US20090221690A1

  公开（公告）日：2009-09-03

  Osteoporosis is one of the major problems in our aging society. Osteoporosis results in bone fracture in older members of the population, especially in post-menopausal women. In traditional medicine, there are many natural crude drugs that have the potential for use to treat bone diseases. So far, there is no report in literature on anti-osteoporosis (bone forming) activity of Butea species. It was thought to study the anti-osteoporotic activity of this plant. Thus, the present invention provides a pharmaceutical composition from the extracts of Butea monosperma for prevention or treatment of bone disorders, process of preparation and use thereof.
• [EN] A PHARMACEUTICAL COMPOSITION FOR THE PREVENTION/TREATMENT OF BONE DISORDERS AND A PROCESS FOR THE PREPARATION THEREOF<br/>[FR] composition pharmaceutique pour la prévention/le traitement de troubles osseux et son processus d'élaboration
  申请人：COUNCIL SCIENT IND RES

  公开号：WO2007099432A2

  公开（公告）日：2007-09-07

  [EN] Osteoporosis is one of the major problems in our aging society. Osteoporosis results in bone fracture in older members of the population, especially in post-menopausal women. In traditional medicine, there are many natural crude drugs that have the potential for use to treat bone diseases. So far, there is no report in literature on anti- osteoporosis (bone forming) activity of Butea species. It was thought to study the anti- osteoporotic activity of this plant. Thus, the present invention provides a pharmaceutical composition from the extracts of Butea monosperma for prevention or treatment of bone disorders, process of preparation and use thereof.
  [FR] L'ostéoporose est l'un des problèmes majeurs de notre société vieillissante. L'ostéoporose se traduit par une fracture des os chez les personnes d'un certain âge, en particulier les femmes ménopausées. Dans la médecine traditionnelle, il existe de nombreux médicaments bruts naturels ayant le potentiel de traiter les maladies osseuses. Jusqu'à présent, la littérature ne fait nullement état de l'activité anti-ostéoporose (de formation osseuse) de l'espèce appelée Butea. On a envisagé l'étude de l'activité anti-ostéoporotique de cette plante. Ainsi, la présente invention porte sur une composition pharmaceutique à base d'extraits de Butea monosperma pour la prévention ou le traitement de troubles osseux, son processus d'élaboration et son utilisation.