12-Oxododec-9-enoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 12-Oxododec-9-enoic acid
• 化学式: C₁₂H₂₀O₃
• 分子量: 212.28
• InChiKey: KIHXTOVLSZRTHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS
  申请人：Elevance Renewable Sciences, Inc.

  公开号：EP3281931A1

  公开（公告）日：2018-02-14

  Described are methods of making organic compounds by metathesis chemistry. The methods of the invention are particularly useful for making industrially-important organic compounds beginning with starting compositions derived from renewable feedstocks, such as natural oils. The methods make use of a cross-metathesis step with an olefin compound to produce functionalized alkene intermediates having a pre-determined double bond position. Once isolated, the functionalized alkene intermediate can be self-metathesized or cross-metathesized (e.g., with a second functionalized alkene) to produce the desired organic compound or a precursor thereto. The method may be used to make bifunctional organic compounds, such as diacids, diesters, dicarboxylate salts, acid/esters, acid/amines, acid/alcohols, acid/aldehydes, acid/ketones, acid/halides, acid/nitriles, ester/amines, ester/alcohols, ester/aldehydes, ester/ketones, ester/halides, ester/nitriles, and the like.

  本发明描述了通过偏合成化学制造有机化合物的方法。本发明的方法特别适用于从可再生原料（如天然油）中提取的起始组合物开始制造工业上重要的有机化合物。这些方法利用与烯烃化合物的交叉甲基化步骤，生成具有预定双键位置的官能化烯中间体。一旦分离出来，官能化烯中间体可进行自甲基化或交叉甲基化（例如与第二种官能化烯），以生产所需的有机化合物或其前体。该方法可用于制造双官能团有机化合物，如二酸、二酯、二羧酸盐、酸/酯、酸/胺、酸/醇、酸/醛、酸/酮、酸/卤化物、酸/腈、酯/胺、酯/醇、酯/醛、酯/酮、酯/卤化物、酯/腈等。
• Methods of making organic compounds by metathesis
  申请人：Wilmar Trading Pte Ltd

  公开号：US10906861B2

  公开（公告）日：2021-02-02

  Described are methods of making organic compounds by metathesis chemistry. The methods of the invention are particularly useful for making industrially-important organic compounds beginning with starting compositions derived from renewable feedstocks, such as natural oils. The methods make use of a cross-metathesis step with an olefin compound to produce functionalized alkene intermediates having a pre-determined double bond position. Once isolated, the functionalized alkene intermediate can be self-metathesized or cross-metathesized (e.g., with a second functionalized alkene) to produce the desired organic compound or a precursor thereto. The method may be used to make bifunctional organic compounds, such as diacids, diesters, dicarboxylate salts, acid/esters, acid/amines, acid/alcohols, acid/aldehydes, acid/ketones, acid/halides, acid/nitriles, ester/amines, ester/alcohols, ester/aldehydes, ester/ketones, ester/halides, ester/nitriles, and the like.

  本发明描述了通过偏合成化学制造有机化合物的方法。本发明的方法特别适用于从可再生原料（如天然油）中提取的起始组合物开始制造工业上重要的有机化合物。这些方法利用与烯烃化合物的交叉甲基化步骤，生成具有预定双键位置的官能化烯中间体。一旦分离出来，官能化烯中间体可进行自甲基化或交叉甲基化（例如与第二种官能化烯），以生产所需的有机化合物或其前体。该方法可用于制造双官能团有机化合物，如二酸、二酯、二羧酸盐、酸/酯、酸/胺、酸/醇、酸/醛、酸/酮、酸/卤化物、酸/腈、酯/胺、酯/醇、酯/醛、酯/酮、酯/卤化物、酯/腈等。
• Hydroperoxide lyase polypeptides
  申请人：Pioneer Hi-Bred International, Inc.

  公开号：US20010007156A1

  公开（公告）日：2001-07-05

  Compositions and methods for enhancing disease resistance, and modulating levels of flavor molecules in plants are provided. The compositions comprise nucleotide sequences encoding maize HPL genes. The methods comprise expressing hydroperoxide lyase (HPL) genes in plants, plant cells, and plant tissues. Expression cassettes comprising the HPL sequences of the invention are provided, as well as transformed plant cells, plant tissues, and plants.

  本发明提供了用于增强植物抗病性和调节风味分子水平的组合物和方法。这些组合物包括编码玉米 HPL 基因的核苷酸序列。这些方法包括在植物、植物细胞和植物组织中表达氢过氧化物裂解酶（HPL）基因。提供了包含本发明HPL序列的表达盒以及转化的植物细胞、植物组织和植物。
• Hydroperoxide lyase gene from maize and methods of use
  申请人：Pioneer Hi-Bred International, Inc.

  公开号：US20030167510A1

  公开（公告）日：2003-09-04

  Compositions and methods for enhancing disease resistance, and modulating levels of flavor molecules in plants are provided. The compositions comprise nucleotide sequences encoding maize HPL genes. The methods comprise expressing hydroperoxide lyase (HPL) genes in plants, plant cells, and plant tissues. Expression cassettes comprising the HPL sequences of the invention are provided, as well as transformed plant cells, plant tissues, and plants.

  本发明提供了用于增强植物抗病性和调节风味分子水平的组合物和方法。这些组合物包括编码玉米 HPL 基因的核苷酸序列。这些方法包括在植物、植物细胞和植物组织中表达氢过氧化物裂解酶（HPL）基因。提供了包含本发明HPL序列的表达盒以及转化的植物细胞、植物组织和植物。
• Lipoxygenase overexpression in plants and reduction in plant sensitivity to diseases and to attacks from pathogenic organisms
  申请人：——

  公开号：US20040205842A1

  公开（公告）日：2004-10-14

  The present invention relates to methods for reducing plant sensitivity to diseases and attacks from pathogenic organisms. The methods according to the invention comprises overexpressing an inducible lipoxygenase in plants in order to improve their response to diseases and pathogens. The invention also relates to expression cassettes for overexpressing lipoxygenases in plants, and also to transformed plants.

  本发明涉及降低植物对病害和病原生物攻击敏感性的方法。根据本发明的方法，包括在植物中过表达诱导型脂氧合酶，以改善植物对疾病和病原体的反应。本发明还涉及在植物中过表达脂氧合酶的表达盒，以及转化植物。