6-[3,4,5-Trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexane-1,2,3,4,5-pentol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-[3,4,5-Trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexane-1,2,3,4,5-pentol
• 化学式: C₁₈H₃₄O₁₆
• 分子量: 506.5
• InChiKey: KMNMNIBWPCHYPW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -7.4
• 重原子数：
  34
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  280
• 氢给体数：
  12
• 氢受体数：
  16

文献信息

• Polyol and Polyether Iron Oxide Complexes as Pharmacological and/or MRI Contrast Agents
  申请人：Groman Ernest V.

  公开号：US20110144054A1

  公开（公告）日：2011-06-16

  Pharmacological compositions, and methods for administration, of the type employing an iron oxide complex with a polyol or polyether. The methods of administration may comprise parenteral administration of an effective dose of the complex formulated in a biocompatible liquid delivered at a rate of from about 1 mL/sec to less than 1 mL/min and wherein upon administration the complex provides minimal detectable free iron in a subject, and minimal incidence of anaphylaxis. The pharmacological compositions are of the type employing a polyol or polyether iron oxide complex, which, upon parenteral administration to a subject, are substantially immunosilent, provide minimal anaphylaxis and minimal free iron, and undergo minimal dissolution in vivo.
• CRYOPROTECTING AGENT, CRYOPROTECTING AND CRYOPRESERVED COMPOSITIONS, USES THEREOF, AND METHODS OF CRYOPRESERVATION
  申请人：PHARMACOSMOS A/S

  公开号：US20150320031A1

  公开（公告）日：2015-11-12

  The present invention relates to a cryoprotecting agent comprising a cryprotectant being one or more of: dextrin, dextran, isomaltooligosaccharide and derivatives thereof, cryoprotecting and cryopreserved compositions, uses thereof, and methods of cryopreservation.
• US7553479B2
  申请人：——

  公开号：US7553479B2

  公开（公告）日：2009-06-30
• US7871597B2
  申请人：——

  公开号：US7871597B2

  公开（公告）日：2011-01-18
• US8501158B2
  申请人：——

  公开号：US8501158B2

  公开（公告）日：2013-08-06