Zinc nicotinate | 51914-60-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Zinc nicotinate
• 英文别名: zinc;pyridine-3-carboxylate
• CAS: 51914-60-4
• 化学式: C12H8N2O4Zn
• 分子量: 309.6
• InChiKey: VYAAXNAPTXCMLY-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -1.11
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  106
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  烟酸 、 zinc acetate 、 ammonium hydroxide 在 5B 、 水 作用下， 以 水 为溶剂， 反应 0.17h， 以to obtain 3.0 g of zinc nicotinate (的产率得到Zinc nicotinate
  参考文献：
  名称：

  Remedy for dermatopathy and metallothionein inducer

  摘要：

  选择自烟酰胺、吡啶酰胺、3,4-二羟基苯甲酸、氨基酸、肽、桧木酚和以式(1)表示的吡啶羧酸的化合物的锌盐、锌络合物或其盐具有金属硫蛋白诱导作用、抑制晒伤细胞产生的效果，因此，可用作化妆品和药物，用于改善晒伤、预防晒伤、改善皮肤疾病、缓解辐射障碍等。

  公开号：

  US05582817A1

文献信息

• Antibacterial and antifungal activity method, therapeutic method of
  申请人：Otsuka Pharmaceutical Co., Ltd.

  公开号：US05696169A1

  公开（公告）日：1997-12-09

  The present invention provides a method of controlling bacteria or fungi which comprises contacting therewith a zinc compound and at least one member selected from among hinokitiol and salts thereof; a method of treating infectious diseases caused by bacteria or fungi which comprises administering a zinc compound and at least one member selected from among hinokitiol and salts thereof; and a method of preserving cosmetics which comprises adding thereto a zinc compound and at least one member selected from among hinokitiol and salts thereof.

  本发明提供了一种控制细菌或真菌的方法，包括与锌化合物和至少一种从桧木酚及其盐中选择的成员接触；一种治疗由细菌或真菌引起的传染病的方法，包括给予锌化合物和至少一种从桧木酚及其盐中选择的成员；以及一种保护化妆品的方法，包括添加锌化合物和至少一种从桧木酚及其盐中选择的成员。
• REMEDY FOR DERMATOPATHY AND METALLOTHIONEIN INDUCER
  申请人：OTSUKA PHARMACEUTICAL CO., LTD.

  公开号：EP0583479A1

  公开（公告）日：1994-02-23

  A zinc salt, a zinc complex or a zinc complex salt of a compound selected from among a pyridine-carboxylic acid represented by general formula (1), nicotinamide, picolinamide, 3,4-dihydroxybenzoic acid, an amino acid, a peptide and hinokitiol has the effects of inducing metallothionein and inhibiting sunburn cell production, thus being useful as a cosmetic or medicine for treating or preventing sunburn and treating dermatopathy, radiation damage or the like.

  选自通式（1）代表的吡啶-羧酸、烟酰胺、吡啶酰胺、3,4-二羟基苯甲酸、氨基酸、肽和桧醇中的化合物的锌盐、锌络合物或锌络合物盐具有诱导金属硫蛋白和抑制晒伤细胞生成的作用，因此可用作治疗或预防晒伤和治疗皮肤病、辐射损伤或类似疾病的化妆品或药物。
• METHOD OF TREATING INFECTIOUS DISEASE, METHOD OF PREVENTING PUTREFACTION OF COSMETIC, AND ANTIBACTERIAL/ANTIFUNGAL AGENT AND COSMETIC
  申请人：OTSUKA PHARMACEUTICAL CO., LTD.

  公开号：EP0589047A1

  公开（公告）日：1994-03-30

  A method of treating infectious diseases caused by bacteria or fungi by administering a zinc compound and at least one compound selected from the group consisting of hinokitiol and salts thereof; a method of preventing putrefaction of cosmetics by adding thereto a zinc compound and at least one compound selected from the group consisting of hinokitiol and salts thereof; and antibacterial/antifungal agents and cosmetics each containing a zinc compound and at least one compound selected from the goup consisting of hinokitiol and salts thereof.

  一种通过施用锌化合物和至少一种选自桧皮酚及其盐类的化合物来治疗由细菌或真菌引起的传染性疾病的方法；一种通过在化妆品中添加锌化合物和至少一种选自桧皮酚及其盐类的化合物来防止化妆品腐败的方法；以及含有锌化合物和至少一种选自桧皮酚及其盐类的化合物的抗菌/抗真菌剂和化妆品。
• Nutritional additives containing cranberry extract for the digestive system and their uses
  申请人：Laboratoires SANTINOV

  公开号：EP2133121A1

  公开（公告）日：2009-12-16

  This invention relates to the necessities of the life and namely to the nutrition. It has as the subject matter a nutritional supplement intended to prevent or to counteract the recurring gastric discomfort which contain as the active ingredient a cranberry extract titrated in polymeric proanthocyanidines in a solid or liquid carrier suitable for oral administration. Use of the said nutritional supplement in digestive surgery, to eliminate Helicobacter pylori in the digestive system, in order to contribute to sustain the normal secretion of gastric mucus and contribute to maintain the integrity of the mucosal protective barrier.

  本发明涉及生活必需品，即营养。 本发明的主题是一种营养补充剂，旨在预防或消除反复出现的胃部不适，其有效成分为蔓越莓提取物，滴定在适合口服的固体或液体载体中的聚合原花青素中。 在消化系统手术中使用上述营养补充剂，以消除消化系统中的幽门螺旋杆菌，从而有助于维持胃粘膜的正常分泌，并有助于保持粘膜保护屏障的完整性。
• Synergistic antimicrobial composition of zinc pyrithione
  申请人：Jubilant Life Sciences Limited

  公开号：US10314312B2

  公开（公告）日：2019-06-11

  The present invention discloses synergistic antimicrobial composition comprises zinc pyrithione and a zinc salt of pyridine carboxylic acid.

  本发明公开了由吡硫锌和吡啶甲酸锌盐组成的协同抗菌组合物。