2-[(Pyridine-3-carbonyl)-amino]-succinic acid | 13839-28-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[(Pyridine-3-carbonyl)-amino]-succinic acid
• 英文别名: N-(pyridin-3-ylcarbonyl)aspartic acid；2-(pyridine-3-carbonylamino)butanedioic acid
• CAS: 13839-28-6
• 化学式: C₁₀H₁₀N₂O₅
• 分子量: 238.2
• InChiKey: LSIRGZKVRFDTNG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  117
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME
  申请人：Kempharm, Inc.

  公开号：EP2736510A2

  公开（公告）日：2014-06-04
• [EN] METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME<br/>[FR] PROMÉDICAMENTS MÉTHYLPHÉNIDATES, PROCÉDÉS DE FABRICATION ET D'UTILISATION DE CEUX-CI
  申请人：KEMPHARM INC

  公开号：WO2013016668A2

  公开（公告）日：2013-01-31

  The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.