Enalaprilat-D5 (phenyl-D5)

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Enalaprilat-D5 (phenyl-D5)
• 英文别名: 1-[2-[(1-carboxy-3-phenylpropyl)amino]propanoyl]pyrrolidine-2-carboxylic acid
• 化学式: C₁₈H₂₄N₂O₅
• 分子量: 348.4
• InChiKey: LZFZMUMEGBBDTC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  25
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  107
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• BIOSENSING PLATFORM FOR DETECTING VIRAL INFECTIONS AND METHODS FOR SCREENING A MODULATOR OF VIRAL INFECTIONS AND PROTECTING THEREFROM
  申请人：PD BIOMEDICAL CO., LTD.

  公开号：US20220117936A1

  公开（公告）日：2022-04-21

  Provided is a method for screening a modulator of a viral infection by detecting an interaction of angiotensin converting enzyme 2 (ACE2) and a spike protein with a biosensing platform. Also provided is a compound of formula (I) as a modulator of a viral infection, where R, X, A, R 3 to R 5 , and m are as defined herein, and a method for protecting a subject from a viral infection by administering with the compound.
• [EN] BIOSENSING PLATFORM FOR DETECTING VIRAL INFECTIONS AND METHODS FOR SCREENING A MODULATOR OF VIRAL INFECTIONS AND PROTECTING THEREFROM<br/>[FR] PLATEFORME DE BIODÉTECTION POUR DÉTECTER DES INFECTIONS VIRALES ET PROCÉDÉS DE CRIBLAGE D'UN MODULATEUR D'INFECTIONS VIRALES ET DE PROTECTION CONTRE CELLES-CI
  申请人：[en]PD BIOMEDICAL CO., LTD.

  公开号：WO2022083644A1

  公开（公告）日：2022-04-28

  Provided is a method for screening a modulator of a viral infection by detecting an interaction of angiotensin converting enzyme 2 (ACE2) and a spike protein with a biosensing platform. Also provided is a compound of formula (I) as a modulator of a viral infection, where R, X, A, R3to R5, and m are as defined herein, and a method for protecting a subject from a viral infection by administering with the compound.