N-[5-[acetyl(hydroxy)amino]pentyl]-N'-[5-[[4-[(4-amino-3-fluorobutyl)-hydroxyamino]-4-oxobutanoyl]amino]pentyl]-N'-hydroxybutanediamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-[5-[acetyl(hydroxy)amino]pentyl]-N'-[5-[[4-[(4-amino-3-fluorobutyl)-hydroxyamino]-4-oxobutanoyl]amino]pentyl]-N'-hydroxybutanediamide
• 化学式: C₂₄H₄₅FN₆O₈
• 分子量: 564.6
• InChiKey: MJCVDZWRAWGJEN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.4
• 重原子数：
  39
• 可旋转键数：
  22
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  206
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• [EN] NOVEL ANALOGUES OF DESFERRIOXAMINE B (DFOB)<br/>[FR] NOUVEAUX ANALOGUES DE DÉFÉROXAMINE B (DFOB)
  申请人：UNIV SYDNEY

  公开号：WO2017152237A1

  公开（公告）日：2017-09-14

  The present invention relates to new Desferrioxamine B-based compounds that are useful for iron-chelation therapy, to their preparation, and to compositions including the compounds. The present invention also relates to the use of the compounds, as well as compositions including the compounds, in the treatment of conditions of iron dyshomeostasis.