4,4'-dibenzoyl-1,1'-biphenyl | 33090-29-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4'-dibenzoyl-1,1'-biphenyl
• 英文别名: 4,4'-dibenzoyldiphenyl；4,4'-dibenzoylbiphenyl；biphenyl-4,4'-diyl bis(phenyl methanone)；[4-(4-Benzoylphenyl)phenyl](phenyl)methanone；[4-(4-benzoylphenyl)phenyl]-phenylmethanone
• CAS: 33090-29-8
• 化学式: C₂₆H₁₈O₂
• 分子量: 362.428
• InChiKey: MLNFAVZUSGIURZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  28
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4,4'-dibenzoyl-1,1'-biphenyl 在 盐酸 、 乙醚 、 乙酰氯 、 苯 作用下， 生成 4,4'-bis(diphenylchloromethyl)biphenyl
  参考文献：
  名称：

  Schlenk; Brauns, Chemische Berichte, 1915, vol. 48, p. 727

  摘要：

  DOI：
• 作为产物：
  描述：

  联苯胺 在 盐酸 、 乙醚 、 sodium nitrite 、 苯 作用下， 生成 4,4'-dibenzoyl-1,1'-biphenyl
  参考文献：
  名称：

  The Preparation of 4,4'-Dicyano-diphenyl and Certain Diketones of Diphenyl

  摘要：

  DOI：

  10.1021/ja01865a014
• 作为试剂：
  描述：

  联苯 、 苯甲酰氯 、 三氯化铝 、 盐酸 在 水 、 正己烷 、 4,4'-dibenzoyl-1,1'-biphenyl 、 氯仿 作用下， 以 硝基苯 为溶剂， 反应 3.58h， 生成 4,4'-dibenzoyl-1,1'-biphenyl
  参考文献：
  名称：

  Photoinitiators and oxygen scavenging compositions

  摘要：

  提供了一种含有氧气清除材料、光引发剂和至少一种催化剂的氧气清除组合物或系统，其中光引发剂包含至少两个苯甲酮基团的苯甲酮衍生物，且至少一种催化剂能够催化氧气清除反应。还提供了一种薄膜、多相组合物、多层组合物、多层薄膜、含有氧气清除组合物的物品、制备氧气清除组合物的方法以及清除氧气的方法。还提供了非可提取苯甲酮衍生物光引发剂及其制备方法。

  公开号：

  US06139770A1

文献信息

• Miyaura Borylations of Aryl Bromides in Water at Room Temperature
  作者：Bruce H. Lipshutz、Ralph Moser、Karl R. Voigtritter

  DOI：10.1002/ijch.201000045

  日期：2010.12

  New technology for palladium‐catalyzed cross‐couplings between B2pin2 and aryl bromides leading to arylboronates is described. Micellar catalysis serves to enable borylations to take place in water as the only medium at ambient temperatures.

  描述了钯催化 B 2 pin 2和芳基溴化物之间交叉偶联产生芳基硼酸酯的新技术。胶束催化作用是使硼酸化能够在环境温度下在作为唯一介质的水中发生。
• METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND
  申请人：Oda Seiji

  公开号：US20110275859A1

  公开（公告）日：2011-11-10

  A method for manufacturing a conjugated aromatic compound comprising reacting an aromatic compound (A) wherein one or two leaving groups selected from the group consisting of an iodine atom, a bromine atom and a chlorine atom are bonded to an aromatic ring and the aromatic compound (A) does not have (c1) a group represented by the following formula (10): wherein A 1 represents a C1-C20 alkoxy group etc.; (g1) a C1-C20 alkyl group which may be substituted with a fluorine atom etc.; and (h1) a C2-C20 acyl group which may be substituted with a fluorine atom etc., at the neighboring carbon atom to the carbon atom to which the leaving group is bonded, with an aromatic compound (A) having the same structure as that of the above-mentioned aromatic compound (A) or an aromatic compound (B) wherein the aromatic compound (B) is structurally different from the above-mentioned aromatic compound (A), one or two leaving groups selected from the group consisting of an iodine atom, a bromine atom and a chlorine atom are bonded to an aromatic ring and the aromatic compound (B) does not have the above-mentioned (c1), (g1) and (h1) at the neighboring carbon atom to the carbon atom to which the leaving group is bonded, in the presence of (i) a nickel compound, (ii) a metal reducing agent, (iii) at least one ligand (L1) selected from the group consisting of a 2,2′-bipyridine compound having at least one electron-withdrawing group and having no substituent at 3-, 6-, 3′- and 6′-positions, and a 1,10-phenanthroline compound having at least one electron-withdrawing group and having no substituent at 2- and 9-positions, and (iv) at least one ligand (L2) selected from the group consisting of a 2,2′-bipyridine compound having at least one electron-releasing group and having no substituent at 3-, 6-, 3′- and 6′-positions, and a 1,10-phenanthroline compound having at least one electron-releasing group and having no substituent at 2- and 9-positions.

  一种制备共轭芳香化合物的方法，包括将含有一个或两个离去基团的芳香化合物（A）与含有相同结构的上述芳香化合物（A）或结构不同的芳香化合物（B）反应，其中这些离去基团选自碘原子、溴原子和氯原子，与芳香环结合，而芳香化合物（A）没有以下式（10）所代表的基团：其中A1代表C1-C20烷氧基等；（g1）代表C1-C20烷基基团，可能被氟原子等取代；以及（h1）代表C2-C20酰基基团，可能被氟原子等取代，与离去基团结合的碳原子的相邻碳原子处没有上述（c1）、（g1）和（h1），在（i）镍化合物、（ii）金属还原剂、（iii）从2,2′-联吡啶化合物和1,10-邻菲啰啉化合物中选择的至少一种配体（L1），具有至少一个吸电子基团且在3-、6-、3′-和6′-位置没有取代基，以及（iv）从2,2′-联吡啶化合物和1,10-邻菲啰啉化合物中选择的至少一种配体（L2），具有至少一个释电子基团且在3-、6-、3′-和6′-位置没有取代基团的情况下，在上述离去基团结合的碳原子的相邻碳原子处进行反应。
• Biaryl Diketone Synthesis via Palladium-catalyzed Carbonylative Coupling with Carbon Monoxide or Various Metal Carbonyls
  作者：Soo Kyung Cho、Ju Hyun Song、Jung Tae Hahn、Dai il Jung

  DOI：10.1002/bkcs.10904

  日期：2016.10

  carbonylative coupling in the presence of a palladium N‐heterocyclic carbene complex and CO or metal carbonyls. Different arylboronic acids along with various CO‐releasing molecules were tested to study the influence of structure. Generally, steric hindrance of arylboronic acids and CO‐releasing ability of various metal carbonyls played significant roles. In most cases, single ketone products were found as the

  在钯N-杂环卡宾配合物和CO或金属羰基化合物的存在下，通过钯催化的羰基化偶联合成联芳基二酮。测试了不同的芳基硼酸以及各种释放CO的分子，以研究结构的影响。通常，芳基硼酸的位阻和各种羰基金属的CO释放能力起着重要作用。在大多数情况下，发现单酮产品是副产品，而不是直接偶联产品。
• Palladium(II) chloride/EDTA-catalyzed biaryl homo-coupling of aryl halides in aqueous medium in the presence of ascorbic acid
  作者：Ram N. Ram、Virinder Singh

  DOI：10.1016/j.tetlet.2006.08.056

  日期：2006.10

  Both electron-deficient and electron-rich aryl bromides undergo biaryl homo-coupling in a basic aqueous-ethanolic medium in the presence of PdCl2–EDTA (1:1 molar ratio, 3 mol %) as catalyst and ascorbic acid as reductant (1 mol equiv) in acceptable to good yields.

  缺电子和富电子芳基溴化物都在碱性含水乙醇介质中，在作为催化剂的PdCl 2 -EDTA（1：1摩尔比，3 mol％）和抗坏血酸作为还原剂（1的情况下）发生联芳基均偶联。摩尔当量）以可接受的良好收率。
• Visible Light-Driven, Gold(I)-Catalyzed Preparation of Symmetrical (Hetero)biaryls by Homocoupling of Arylazo Sulfones
  作者：Lorenzo Di Terlizzi、Simone Scaringi、Carlotta Raviola、Riccardo Pedrazzani、Marco Bandini、Maurizio Fagnoni、Stefano Protti

  DOI：10.1021/acs.joc.2c00225

  日期：2022.4.1

  The preparation of symmetrical (hetero)biaryls via arylazo sulfones has been successfully carried out upon visible light irradiation in the presence of PPh3AuCl as the catalyst. The present protocol led to the efficient synthesis of a wide range of target compounds in an organic-aqueous solvent under photocatalyst-free conditions.

  在PPh 3 AuCl作为催化剂的情况下，在可见光照射下成功地通过芳基偶氮砜制备了对称（杂）联芳基化合物。本方案可以在无光催化剂的条件下在有机水溶剂中有效合成多种目标化合物。