2-[(2-Amino-3-methylbutanoyl)amino]butanedioic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[(2-Amino-3-methylbutanoyl)amino]butanedioic acid
• 化学式: C₉H₁₆N₂O₅
• 分子量: 232.23
• InChiKey: OBTCMSPFOITUIJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.7
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  130
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• US5302582A
  申请人：——

  公开号：US5302582A

  公开（公告）日：1994-04-12
• [EN] DETECTION OF COLORECTAL CANCER WITH TWO NOVEL HEME-RELATED MOLECULES IN HUMAN FECES<br/>[FR] DÉTECTION D'UN CANCER COLORECTAL, AVEC DEUX NOUVELLES MOLÉCULES DE TYPE HÈME DANS DES FÈCES HUMAINES
  申请人：US HEALTH

  公开号：WO2016003893A1

  公开（公告）日：2016-01-07

  The present invention provides a method of assessing the presence or absence of CRC or CRA in a patient. The method involves obtaining a stool sample from the patient and assaying the stool sample to detect the presence or absence of one or both of two peptides referred to herein as X-18565 and X-19549. In another embodiment, the present invention provides an immunogenically-stimulatory composition comprising one or both of X-18565 and X-19549, including a physiologically-acceptable carrier. The invention also provides a method for producing antibodies that can specifically bind to X-18565 and X-19549, respectively, by administering such compositions to animals, which are thereby induced to produce antibodies. In another embodiment, the present invention provides a composition comprising an specific binding partner to either or both of X-18565 and X-19549 and to diagnostic test kits employing such reagents.