4-(2-Chloroethyl)-1-[cyclohex-2-en-1-yl(hydroxy)methyl]-5-ethyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-(2-Chloroethyl)-1-[cyclohex-2-en-1-yl(hydroxy)methyl]-5-ethyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione
• 化学式: C₁₆H₂₂ClNO₄
• 分子量: 327.8
• InChiKey: OHEOUKCSOLOBHI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  75.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Salt formulations for the fermentation of marine microorganisms
  申请人：Triphase Research and Development I Corp.

  公开号：US10011814B2

  公开（公告）日：2018-07-03

  Growth medium are disclosed for use in fermenting a marine microorganism. The medium comprise Potassium, Calcium, Strontium, Borate and Fluoride at specific concentrations. Alternatively, the growth medium comprises cobalt at specified concentrations or comprises vitamin B12 at specified concentrations. Methods of producing certain desired compound by fermentation of a marine microorganism are also disclosed.

  公开了用于海洋微生物发酵的生长培养基。培养基包括特定浓度的钾、钙、锶、硼酸盐和氟化物。另外，生长培养基还包括特定浓度的钴或特定浓度的维生素 B12。还公开了通过海洋微生物发酵生产某些所需化合物的方法。
• Methods of using [3.2.0] heterocyclic compounds and analogs thereof
  申请人：Palladino Michael

  公开号：US20070004676A1

  公开（公告）日：2007-01-04

  Disclosed are methods of treating cancer comprising administering to the animal, a therapeutically effective amount of a heterocyclic compound of Formula VI. The animal is a mammal, preferably a human or a rodent.
• SALT FORMULATIONS FOR THE FERMENTATION OF MARINE MICROORGANISMS
  申请人：Lam Kin Sing

  公开号：US20080160590A1

  公开（公告）日：2008-07-03

  Growth medium are disclosed for use in fermenting a marine microorganism. The medium comprise Potassium, Calcium, Strontium, Borate and Fluoride at specific concentrations. Alternatively, the growth medium comprises cobalt at specified concentrations or comprises vitamin B 12 at specified concentrations. Methods of producing certain desired compound by fermentation of a marine microorganism are also disclosed.
• METHODS OF USING [3.2.0] HETEROCYCLIC COMPOUNDS AND ANALOGS THEREOF IN TREATING WALDENSTROM'S MACROGLOBULINEMIA
  申请人：Ghobrial Irene

  公开号：US20090156469A1

  公开（公告）日：2009-06-18

  Disclosed are methods of treating Waldenstrom's Macroglobulinemia comprising administering to the animal, a therapeutically effective amount of a heterocyclic compound of Formula I.
• BIOSYNTHESES OF SALINOSPORAMIDE A AND ITS ANALOGS AND RELATED METHODS OF MAKING SALINOSPORAMIDE A AND ITS ANALOGS
  申请人：Lam Kin Sing

  公开号：US20090197310A1

  公开（公告）日：2009-08-06

  Disclosed are methods of modulating biosynthesis of Salinosporamide A and its analogs, which are useful in treating cancer, inflammatory conditions, and/or infectious disease. The methods involve, for example, genetic manipulation, selection of reagents in the fermentation feedstock, and selection of fermentation conditions.