(3R,4R)-4-amino-3-[(1-carboxyeth-1-en-1-yl)oxy]cyclohexa-1,5-diene-1-carboxylic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (3R,4R)-4-amino-3-[(1-carboxyeth-1-en-1-yl)oxy]cyclohexa-1,5-diene-1-carboxylic acid
• 英文别名: 4-amino-3-(1-carboxyethenoxy)cyclohexa-1,5-diene-1-carboxylic acid
• 化学式: C₁₀H₁₁NO₅
• 分子量: 225.2
• InChiKey: OIUJHGOLFKDBSU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.3
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  110
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• Rubreserine and its derivates with antiparasitic activity
  申请人：Commissariat à l'Énergie Atomique et aux Énergies Alternatives

  公开号：EP2520297A1

  公开（公告）日：2012-11-07

  The invention relates to novel compounds responding to the following formula (I): or a pharmaceutically acceptable salt thereof, for use as medicaments, and in particular as medicaments for the prevention and/or the treatment of parasitic diseases caused by apicomplexans parasites. The invention also concerns pharmaceutical compositions containing such compounds of formula (I) as active principles. Finally, the present invention relates to the use of compounds of formula (I) as herbicides and/or algaecides and to herbicide and/or algaecide compositions containing such compounds.

  本发明涉及符合下式 (I) 的新型化合物： 或其药学上可接受的盐、 或其药用盐，可用作药物，特别是用作预防和/或治疗由 apicomplexans 寄生虫引起的寄生虫病的药物。本发明还涉及以式（I）化合物为活性成分的药物组合物。最后，本发明涉及式（I）化合物作为除草剂和/或灭藻剂的用途，以及含有此类化合物的除草剂和/或灭藻剂组合物。
• [EN] COMPOUNDS WITH ANTIPARASITIC ACTIVITY AND APPLICATIONS THEREOF<br/>[FR] COMPOSÉS À ACTIVITÉ ANTIPARASITE ET LEURS APPLICATIONS
  申请人：COMMISSARIAT ENERGIE ATOMIQUE

  公开号：WO2012150577A1

  公开（公告）日：2012-11-08

  The invention relates to novel compounds responding to the following formula (I) or a pharmaceutically acceptable salt thereof, for use as medicaments, and in particular as medicaments for the prevention and/or the treatment of parasitic diseases caused by apicomplexans parasites. The invention also concerns pharmaceutical compositions containing such compounds of formula (I) as active principles. Finally, the present invention relates to the use of compounds of formula (I) as herbicides and/or algaecides and to herbicide and/or algaecide compositions containing such compounds.