3-Isopropyl-2,4-pentadien-5-olide | 150669-60-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃
• 英文名称: 3-Isopropyl-2,4-pentadien-5-olide
• 英文别名: 4-propan-2-ylpyran-2-one
• CAS: 150669-60-6
• 化学式: C₈H₁₀O₂
• 分子量: 138.16
• InChiKey: ONGVEHLNILCIKL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• COMPOUNDS FOR THE TREATMENT OF OCULAR CANCER
  申请人：Djaballah Hakim

  公开号：US20130035321A1

  公开（公告）日：2013-02-07

  In one aspect, the instant invention provides novel compounds and pharmaceutical compositions useful for treating proliferative diseases such as cancer. In another aspect, the invention provides methods of using certain compounds in the treatment of proliferative diseases such as cancer. In particular, the instant invention provides methods of treating ocular cancer (e.g., retinoblastoma) using intraarterial infusion to administer inventive compounds locally to the eye of a subject with an ocular cancer.
• US7919487B2
  申请人：——

  公开号：US7919487B2

  公开（公告）日：2011-04-05
• [EN] COMPOUNDS FOR THE TREATMENT OF OCULAR CANCER<br/>[FR] COMPOSÉS POUR LE TRAITEMENT D'UN CANCER OCULAIRE
  申请人：SLOAN KETTERING INST CANCER

  公开号：WO2011068876A1

  公开（公告）日：2011-06-09

  In one aspect, the instant invention provides novel compounds and pharmaceutical compositions useful for treating proliferative diseases such as cancer. In another aspect, the invention provides methods of using certain compounds in the treatment of proliferative diseases such as cancer. In particular, the instant invention provides methods of treating ocular cancer (e.g., retinoblastoma) using intraarterial infusion to administer inventive compounds locally to the eye of a subject with an ocular cancer.