γ-Hydroxy-γ-methyl-glutaminsaeure | 77842-41-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: γ-Hydroxy-γ-methyl-glutaminsaeure
• 英文别名: 2-azaniumyl-4,5-dihydroxy-4-methyl-5-oxopentanoate
• CAS: 77842-41-2
• 化学式: C₆H₁₁NO₅
• 分子量: 177.157
• InChiKey: ONTAOGAXMOTXQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.9
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  121
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Methods for treating of skin conditions with retinoid double conjugate compounds
  申请人：US COSMECEUTECHS LLC

  公开号：US10123960B2

  公开（公告）日：2018-11-13

  A double conjugate molecule made of a retinoid, an organic acid, particularly an a-hydroxy acid, and an alcohol or acyl group, is provided which is useful in treating skin conditions, particularly aging. The retinoid, organic acid, and alcohol/acyl group are preferably linked via ester bonds.

  提供一种由视黄醇、有机酸（特别是α-羟基酸）和醇或酰基组成的双共轭分子，可用于治疗皮肤状况，特别是衰老。视黄醇、有机酸和醇/酰基组最好通过酯键连接。
• Treatment of energy utilization disease
  申请人：Vida Pharma Limited

  公开号：US10842784B2

  公开（公告）日：2020-11-24

  Described are compositions comprising imino sugar acids for the treatment of energy utilization disease (e.g. metabolic syndrome, including any disease or disorder associated therewith, for example central obesity, elevated levels of triglycerides and diabetes, including type 1 diabetes, type 2 diabetes and insulin resistance), processes for producing said compositions from various plant sources, together with various products, compounds, compositions, medical uses and methods based thereon.

  所描述的是包含亚氨基糖酸的组合物，用于治疗能量利用疾病（例如代谢综合征，包括与之相关的任何疾病或紊乱，例如中心性肥胖、甘油三酯水平升高和糖尿病，包括 1 型糖尿病、2 型糖尿病和胰岛素抵抗）；从各种植物来源生产所述组合物的工艺，以及基于此的各种产品、化合物、组合物、医疗用途和方法。
• NEUROTOXIC AMINO ACID OR NEUROTOXIC DERIVATIVE THEREOF ASSOCIATED WITH NEUROLOGICAL DISORDERS
  申请人：Institute For Ethnomedicine

  公开号：EP1664793B1

  公开（公告）日：2007-11-07
• Neurotoxic amino acid or neurotoxic derivative thereof associated with neurological disorders
  申请人：The Institute for Ethnomedicine

  公开号：EP1860441B1

  公开（公告）日：2011-08-10
• FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS
  申请人：Foamix Ltd.

  公开号：EP2097065A2

  公开（公告）日：2009-09-09