2-Oxo-5,8,12-trihydroxy-dodecanoic acid | 29533-15-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 英文名称: 2-Oxo-5,8,12-trihydroxy-dodecanoic acid
• 英文别名: 5,8,12-trihydroxy-2-oxododecanoic acid
• CAS: 29533-15-1
• 化学式: C₁₂H₂₂O₆
• 分子量: 262.3
• InChiKey: OPPXDBWFRYVXHW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  18
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  115
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• PHARMACEUTICAL CARRIERS CAPABLE OF pH DEPENDENT RECONSTITUTION AND METHODS FOR MAKING AND USING SAME
  申请人：PLx Opco Inc.

  公开号：US20220000886A1

  公开（公告）日：2022-01-06

  Disclosed herein are novel drug carriers including a non-aqueous pH dependent release system and a non-aqueous pH dependent reassembly/assembly and reabsorption/absorption system. The carriers are capable of pH dependent release of biologically active agents and assembly or reassembly when the carrier transitions from a low pH environment, to a high pH environment and back to a low pH environment.
• [EN] PHARMACEUTICAL CARRIERS CAPABLE OF pH DEPENDENT RECONSTITUTION AND- METHODS FOR MAKING AND USING SAME<br/>[FR] SUPPORTS PHARMACEUTIQUES APTES À LA RECONSTITUTION DÉPENDANTE DU PH ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION
  申请人：PLX OPCO INC

  公开号：WO2021195319A1

  公开（公告）日：2021-09-30

  Disclosed herein are novel drug carriers including a non-aqueous pH dependent release system and a non-aqueous pH dependent reassembly/assembly and reabsorption/absorption system. The carriers are capable of pH dependent release of biologically active agents and assembly or reassembly when the carrier transitions from a low pH environment, to a high pH environment and back to a low pH environment.