6-Bromo-3-(bromomethyl)-2,3,7-trichloro-7-methyloct-1-ene | 58086-84-3

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 乙烯基卤化物
• 英文名称: 6-Bromo-3-(bromomethyl)-2,3,7-trichloro-7-methyloct-1-ene
• CAS: 58086-84-3
• 化学式: C₁₀H₁₅Br₂Cl₃
• 分子量: 401.4
• InChiKey: OVLCIYBVQSJPKK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• Biomarker:compound correlations in cancer diagnosis and therapy
  申请人：Ross T. Douglas

  公开号：US20050227266A1

  公开（公告）日：2005-10-13

  The present invention provides methods and reagents relating to establishing and using biomarker:chemical compound correlations. The invention provides correlated biomarker:compound pairs, and further provides methods of using such pairs, for example, in the identification of tumors or tumor cells likely to be responsive or resistant to particular therapy, and/or the identification of chemical compounds likely (or unlikely) to be useful in the treatment of particular tumors.

  本发明提供了与建立和使用生物标记物：化合物相关性有关的方法和试剂。本发明提供了相关的生物标记物:化合物对，并进一步提供了使用这些对的方法，例如，用于鉴定可能对特定疗法有反应或有抗药性的肿瘤或肿瘤细胞，和/或鉴定可能（或不可能）用于治疗特定肿瘤的化合物。
• NOVEL ANTITUMOR COMPOUND, COMPOSITIONS AND METHOD OF USE
  申请人：CORNELL RESEARCH FOUNDATION, INC.

  公开号：EP0626937A1

  公开（公告）日：1994-12-07
• US5283383A
  申请人：——

  公开号：US5283383A

  公开（公告）日：1994-02-01
• [EN] NOVEL ANTITUMOR COMPOUND, COMPOSITIONS AND METHOD OF USE
  申请人：THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES

  公开号：WO1993016024A1

  公开（公告）日：1993-08-19

  (EN) The present invention relates to a new antitumor compound, a method for isolating same from a red alga, antitumor compositions containing same and methods of using same for treating patients with cancer. The compound of the present invention is 6(R)-bromo-3(S)-bromomethyl-7-methyl-2,3,7-trichloro-1-octene.(FR) L'invention se rapporte à un nouveau composé antitumoral, à un procédé pour l'isoler d'une algue rouge, à des compositions antitumorales le contenant et à des procédés l'utilisant pour traiter des patients atteints de cancer. Ce composé est le 6(R)-bromo-3(S)-bromométhyle-7-méthyle-3,3,7-trichloro-1-octène.
• [EN] BIOMARKER: COMPOUND CORRELATIONS IN CANCER DIAGNOSIS AND THERAPY<br/>[FR] CORRELATION ENTRE BIOMARQUEURS ET COMPOSES DANS LE DIAGNOSTIC ET LE TRAITEMENT DU CANCER
  申请人：APPLIED GENOMICS INC

  公开号：WO2005085863A2

  公开（公告）日：2005-09-15

  The present invention provides methods and reagents relating to establishing and using biomarker: chemical compound correlations. The invention provides correlated biomarker: compound pairs, and further provides methods of using such pairs, for example, in the identification of tumors or tumor cells likely to be responsive or resistant to particular therapy, and/or the identification of chemical compounds likely (or unlikely) to be useful in the treatment of particular tumors.