1-(4-methoxybenzoyl)-4-methylsulfonyl-N-(2-oxopiperidin-3-yl)piperazine-2-carboxamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1-(4-methoxybenzoyl)-4-methylsulfonyl-N-(2-oxopiperidin-3-yl)piperazine-2-carboxamide
• 化学式: C₁₉H₂₆N₄O₆S
• 分子量: 438.5
• InChiKey: OWMAVPYGJAUCDJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  134
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Cosmetic Use of 1-Aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine Carbomamides and Related Compounds
  申请人：Ptchelintsev Dmitri S.

  公开号：US20100168126A1

  公开（公告）日：2010-07-01

  Cosmetic compositions comprising 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging.
• Cosmetic Use of 1-Aroyl-N-(2-oxo-3-piperidinyl)-2-Piperazine Carbomamides and Related Compounds
  申请人：Ptchelintsev Dmitri S.

  公开号：US20110251213A1

  公开（公告）日：2011-10-13

  Cosmetic compositions comprising 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The 1-aroyl-N-(2-oxo-3-piperidinyl)-2-piperazine carboxamides are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging.
• US7993663B2
  申请人：——

  公开号：US7993663B2

  公开（公告）日：2011-08-09
• US7994175B2
  申请人：——

  公开号：US7994175B2

  公开（公告）日：2011-08-09
• US8168640B2
  申请人：——

  公开号：US8168640B2

  公开（公告）日：2012-05-01