16-methyl-octadecan-1-ol | 2490-01-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 16-methyl-octadecan-1-ol
• 英文别名: 16-methyl-1-octadecanol；16-Methyloctadecan-1-ol
• CAS: 2490-01-9
• 化学式: C₁₉H₄₀O
• 分子量: 284.526
• InChiKey: OZIRXBOVLMZHDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.6
• 重原子数：
  20
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Use of isomonools in the treatment and prophylaxis of cancer
  申请人：DAI-ICHI KOGYO SEIYAKU CO., LTD.

  公开号：EP0452941A2

  公开（公告）日：1991-10-23

  The invention relates to a pharmaceutical composition comprising in admixture with a pharmacologically acceptable carrier at least one isomonool represented by the formula (I): wherein R is an alkyl group with 1 to 5 carbon atoms, and n is an integer of 4 to 22. Said compositions are useful for the treatment and prophylaxis of cancer.

  本发明涉及一种药物组合物，该组合物包含至少一种由式 (I) 代表的异单醇和药理学上可接受的载体： 其中 R 是含有 1 至 5 个碳原子的烷基，n 是 4 至 22 的整数。 所述组合物可用于治疗和预防癌症。
• GEL HAIR COSMETIC
  申请人：Kao Corporation

  公开号：EP2939658A1

  公开（公告）日：2015-11-04

  The invention provides a gel-form hair cosmetic composition, which contains components (a) to (c) emulsified in an aqueous component, and which exhibits an endothermic peak temperature of from 40°C to 75°C as measured through DSC, wherein the components are (a) a polyalkyleneimine derivative or a salt thereof, the polyalkyleneimine derivative being formed of a polyalkyleneimine having a weight average molecular weight of from 3,300 to 50,000, in which one of the substituents of R1-CO-, R1-(CH2)n-CHX-CH2-, and R3-NH-CO- [R1 is H, alkyl, alkenyl, or the like; R2 is H, alkyl, alkoxy, alkenyl or the like; n is 0 or 1; X is H or OH; R3 is H, alkyl, or alkenyl; at least one of R1 to R3 has 13 or more carbon atoms; and the entirety of R1, R2, and R3 has an average number of carbon atoms of 9 or more and a linear group content of 30 mol% or more] is bonded to 40 mol% or more of the nitrogen atoms of the polyalkyleneimine; (b) a C12 to C28 saturated aliphatic alcohol; and (c) a cationic surfactant.

  本发明提供了一种凝胶状头发化妆品组合物，该组合物包含乳化在水性组分中的组分(a)至(c)，通过 DSC 测量，该组合物的内热峰温度为 40°C 至 75°C，其中组分为 (a) 聚亚烷酰亚胺衍生物或其盐、该聚亚烷基亚胺衍生物由重量平均分子量为 3,300 至 50,000 的聚亚烷基亚胺形成，其中 R1-CO-、R1-(CH2)n-CHX-CH2-和 R3-NH-CO- [R1 是 H、烷基、烯基或类似物；R2 是 H、烷基、烷氧基、烯基或类似物；n 是 0 或 1；X 是 H 或 OH；R3 是 H、烷基或烯基；R1 至 R3 中至少有一个具有 13 个或更多碳原子；R1、R2 和 R3 的全部平均碳原子数为 9 个或更多，线性基团含量为 30 摩尔%或更多]与 40 摩尔%或更多的聚亚烷基亚胺的氮原子键合；(b) C12 至 C28 饱和脂肪醇；以及 (c) 阳离子表面活性剂。
• HAIR WASH
  申请人：Kao Corporation

  公开号：EP2939659A1

  公开（公告）日：2015-11-04

  The invention provides a hair cleansing composition which contains the following components (a), (b), and (c), component (a) being in the form of particles having a mean particle size of from 0.5 µm to 50 µm, wherein the components (a), (b), and (c) are: (a) a polyalkyleneimine derivative or a salt thereof, the derivative formed of a polyalkyleneimine having a weight average molecular weight of from 3,300 to 50,000, in which at least one of R1-CO-, R2-(CH2)n-CHX-CH2-, and R3-NH-CO- [wherein R1 represents H, an alkyl, an alkenyl, or the like; R2 represents H, an alkyl, an alkoxy, an alkenyl, or the like; n is 0 or 1; X represents H or OH; R3 represents H, an alkyl, or an alkenyl; and at least one of R1 to R3 is a group having 13 or more carbon atoms; the entirety of R1 to R3 has an average number of carbon atoms of 9 or more and a linear group content of 30 mol% or more] is bonded to 40 mol% or more of the N atoms of the polyalkyleneimine; (b) an anionic surfactant; and (c) a water-soluble cationic polymer.

  本发明提供了一种头发清洁组合物，该组合物含有以下组分(a)、(b)和(c)，组分(a)呈颗粒状，其平均粒径为0.5微米至50微米，其中组分(a)、(b)和(c)是： (a) 聚亚烷酰亚胺衍生物或其盐，该衍生物由重量平均分子量为 3,300 至 50,000 的聚亚烷酰亚胺形成，其中 R1-CO-、R2-(CH2)n-CHX-CH2-、R3-NH-CO-[其中 R1 代表 H、烷基、烯基或类似物；R2 代表 H、烷基、烷氧基、烯基或类似物；其中 R1 代表 H、烷基、烯基或类似物；R2 代表 H、烷基、烷氧基、烯基或类似物；n 为 0 或 1；X 代表 H 或 OH；R3 代表 H、烷基或烯基；且 R1 至 R3 中至少有一个是具有 13 个或更多碳原子的基团；R1 至 R3 的整个基团的平均碳原子数为 9 或更多，且线性基团含量为 30 摩尔%或更多]键合到聚亚烷基亚胺 40 摩尔%或更多的 N 原子上； (b) 阴离子表面活性剂；和 (c) 水溶性阳离子聚合物。
• Method of preparing sustained-release pharmaceutical preparation
  申请人：TAISHO PHARMACEUTICAL CO. LTD

  公开号：EP0222411B1

  公开（公告）日：1991-08-14
• METHOD FOR PRODUCING FATS OR OILS
  申请人：Archer-Daniels-Midland Company

  公开号：EP1383904A1

  公开（公告）日：2004-01-28