o-methylbenzoyl bromide | 20045-96-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: o-methylbenzoyl bromide
• 英文别名: 6-(1-bromocarbonyl)toluene；2-methyl-benzoyl bromide；2-Methyl-benzoylbromid；o-Toluylsaeure-bromid；o-Toluylbromid；2-methylbenzoyl bromide
• CAS: 20045-96-9
• 化学式: C₈H₇BrO
• 分子量: 199.047
• InChiKey: RHMCYKIIVOITAK-UHFFFAOYSA-N

物化性质

• 沸点：
  133-136 °C(Press: 37 Torr)
• 密度：
  1.486±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  o-methylbenzoyl bromide 在 aluminum isopropoxide 、 二甲胺 、 potassium sulfate 、 zinc 2-ethylhexanoate 作用下， 以 环辛烷 为溶剂， 反应 6.17h， 以98.8%的产率得到2-甲基苯甲酰胺
  参考文献：
  名称：

  邻甲苯甲酰胺有机中间体的合成方法

  摘要：

  本发明公开了邻甲苯甲酰胺有机中间体的合成方法，包括如下步骤：在反应容器中加入6‑(1‑溴‑羰基)‑甲苯，环辛烷溶液，控制搅拌速度310‑330rpm,控制溶液温度至30‑36℃，加入二甲胺溶液，在40‑60min时间内分批次加入异丙醇铝，继续反应90‑120min；然后加入硫酸钾溶液，2‑乙基己酸锌粉末，升高温度至40‑47℃，控制搅拌速度210‑230rpm,继续反应160‑190min,用草酸溶液调节pH至8.5‑9，降低温度至5‑10℃，静置30‑50min,用溴化钠溶液洗涤30‑40min,炔丙醇溶液洗涤50‑70min,在甲醚溶液中重结晶，脱水剂脱水，得成品邻甲苯甲酰胺。

  公开号：

  CN108238966A
• 作为产物：
  描述：

  对甲苯甲酸 在 三溴甲基苯砜 、 三苯基膦 作用下， 以 二氯甲烷 为溶剂， 生成 o-methylbenzoyl bromide
  参考文献：
  名称：

  Synthesis and Anti‐Oomycete Activity of 1‐Sulfonyloxy/Acyloxydihydroeugenol Derivatives

  摘要：

  AbstractEndeavor to discover biorational natural products‐based fungicides, two series (26) of novel 1‐sulfonyloxy/acyloxydihydroeugenol derivatives (3a–p and 5a–j) were prepared and assessed for their fungicidal activity against P. capsici Leonian, in vitro. Results of fungicidal activity revealed that, among all compounds, especially compounds 3a, 5c, and 5e displayed the most potent anti‐oomycete activity against P. capsici with EC50 values of 69.33, 68.81, and 67.77 mg/L, respectively. Overall, the anti‐oomycete activities of 1‐acyloxydihydroeugenol derivatives (5a–j) were higher than that of 1‐sulfonyloxydihydroeugenol derivatives (3a–p). It is proved that the introduction of the acyl group at hydroxy position of dihydroeugenol is more beneficial to improve its anti‐oomycete activity than that of the sulfonyl group. These preliminary results will pave the way for further modification of dihydroeugenol in the development of potential new fungicides.

  DOI：

  10.1002/cbdv.202100329

文献信息

• Electroreductive Coupling of Aromatic Acyl Bromides to 1,2-Diketones
  作者：Naoki Kise、Nasuo Ueda

  DOI：10.1246/bcsj.74.755

  日期：2001.4

  The direct electroreduction of aromatic acyl bromides gave aromatic 1,2-diketones. The best result was obtained using a Pb cathode in acetonitrile containing Bu4NClO4 as a supporting electrolyte. Aromatic acyl bromides substituted by an electron-donating group afforded 1,2-diketones in moderate-to-good yields, whereas acylated endiols were formed exclusively from aromatic acyl bromides substituted by an electron-withdrawing group.

  芳香酰溴的直接电还原反应生成了芳香1,2-二酮。在含有四丁基高氯酸铵作为支持电解质的乙腈中，使用铅阴极获得了最佳结果。带有供电子基团的芳香酰溴能够以中等至良好的产率生成1,2-二酮，而带有吸电子基团的芳香酰溴则仅生成酰基化内二醇。
• Compositions and methods of combatting bacteria and fungi using
  申请人：Kumiai Chemical Industry Co., Ltd.

  公开号：US03937840A1

  公开（公告）日：1976-02-10

  An agricultural germicide having the formula ##SPC1## Wherein R represents C.sub.1-12 alkyl, alkenyl, alkynyl, benzyl or chlorobenzyl.

  一种农业杀菌剂，其化学式为##SPC1##其中R代表C.sub.1-12烷基，烯基，炔基，苄基或氯苄基。
• METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF
  申请人：Kuramoto Ayako

  公开号：US20120130089A1

  公开（公告）日：2012-05-24

  The present invention is directed to provide an efficient production method which is capable of not only obtaining a cyclic sulfonic acid ester (sultone) at low cost and in high yield, but also the sulfonic acid ester (sultone) stably even in a commercial scale. The present invention relates to a method for producing hydroxysultone comprising a first step where a diol having a specified structure and a thionyl halide are reacted to obtain a cyclic sulfite having a specified structure, and a second step where the cyclic sulfite is reacted with water or/and alcohol; a method for producing an unsaturated sultone having a specified structure comprising a third step where a hydroxylsultone having a specified structure is reacted with an acid halide or an acid anhydride to obtain an intermediate, subsequently the intermediate is treated with a base; as well as a cyclic sulfite having a specified structure.

  本发明旨在提供一种高效的生产方法，该方法不仅能够以低成本和高产率获得环状磺酸酯（磺酮），而且能够在商业规模下稳定地生产磺酸酯（磺酮）。本发明涉及一种生产羟基磺酮的方法，包括第一步，其中将具有特定结构的二元醇和硫酰卤反应，以获得具有特定结构的环状亚磺酸酯，以及第二步，其中将环状亚磺酸酯与水或/和醇反应；一种生产具有特定结构的不饱和磺酮的方法，包括第三步，其中将具有特定结构的羟基磺酮与酸卤或酸酐反应，以获得中间体，随后用碱处理中间体；以及具有特定结构的环状亚磺酸酯。
• Agricultural substituted 2-methylbenzanilide germicide
  申请人：Kumiai Chemical Industry Co., Ltd.

  公开号：US03985804A1

  公开（公告）日：1976-10-12

  An agricultural germicide having the formula ##SPC1## Wherein R represents C.sub.1.sub.-12 alkyl, alkenyl, alkynyl, benzyl or chlorobenzyl.

  一种农业杀菌剂，其化学式为 ##SPC1## 其中R代表C.sub.1.sub.-12烷基，烯基，炔基，苯甲基或氯苯甲基。
• Primer, conductor foil with resin, laminated sheet and method of manufacturing laminated sheet
  申请人：Tanaka Kenji

  公开号：US20070185297A1

  公开（公告）日：2007-08-09

  The invention aims to provide a resin primer which can stick an insulator layer to a conductor foil whereof the surface is not much roughened with sufficient adhesive force, a conductor foil with resin, a laminated sheet and a method of manufacturing same. The resin primer of the invention comprises a resin having film-forming ability and a breaking energy of 0.15 J or more. The conductor foil with resin of the invention comprises a resin layer comprising a conductor foil and the aforesaid resin primer. Further, the laminated sheet of the invention comprises the conductor foil, an insulating layer disposed facing the conductor foil, and a resin layer comprising the aforesaid resin primer disposed between the conductor foil and insulating layer so that it is in contact therewith. This laminated sheet can be manufactured by heating and pressurizing a laminate comprising the aforesaid conductor foil with resin, and a prepreg laminated on this resin layer.

  本发明旨在提供一种树脂底漆，其能够将绝缘层粘附到表面未经过多粗糙处理的导电箔上，并具有足够的粘合力，以及一种带有树脂的导电箔、一种层压板和制造方法。本发明的树脂底漆包括具有成膜能力和0.15 J或更高断裂能的树脂。本发明的带有树脂的导电箔包括导电箔和上述树脂底漆组成的树脂层。此外，本发明的层压板包括导电箔、面向导电箔的绝缘层和包括上述树脂底漆的树脂层，该树脂层位于导电箔和绝缘层之间，与其接触。可以通过加热和加压由上述带有树脂的导电箔和预浸料层压制成的层压板来制造该层压板。