(2S,4S)-2-(4-methoxyphenyl)-tetrahydro-2H-4-pyranol | 1026692-65-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (2S,4S)-2-(4-methoxyphenyl)-tetrahydro-2H-4-pyranol
• 英文别名: (2S,4S)-2-(4-methoxyphenyl)oxan-4-ol
• CAS: 1026692-65-8
• 化学式: C₁₂H₁₆O₃
• 分子量: 208.257
• InChiKey: VRHVRTZELLKHAH-JQWIXIFHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-(4-甲氧基苯基)二氢-2H-吡喃-4(3h)-酮 在 Daucus carota cells 作用下， 以 水 为溶剂， 反应 30.0h， 生成 (2R,4S)-2-(4-methoxyphenyl)-tetrahydro-2H-4-pyranol 、 (2R,4R)-2-(4-methoxyphenyl)-tetrahydro-2H-4-pyranol 、 (2S,4R)-2-(4-methoxyphenyl)-tetrahydro-2H-4-pyranol 、 (2S,4S)-2-(4-methoxyphenyl)-tetrahydro-2H-4-pyranol
  参考文献：
  名称：

  Enantioselective reduction of 2-substituted tetrahydropyran-4-ones using Daucus carota plant cells

  摘要：

  Enzymatic reduction of 2-substituted tetrahydropyran-4-ones with Daucus carota, plant cells as biocatalyst occurred in water under extremely mild and environmentally benign conditions giving a 1:1 mixture of diastereoselectively (2R,4S)- and (2S,4S)-2-aryl- or 2-alkyl-tetrahydropyranois in high yields. (c) 2008 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2008.02.131

文献信息

• Enantioselective reduction of 2-substituted tetrahydropyran-4-ones using Daucus carota plant cells
  作者：J.S. Yadav、B.V. Subba Reddy、Ch. Sreelakshmi、G.G.K.S. Narayana Kumar、A. Bhaskar Rao

  DOI：10.1016/j.tetlet.2008.02.131

  日期：2008.4

  Enzymatic reduction of 2-substituted tetrahydropyran-4-ones with Daucus carota, plant cells as biocatalyst occurred in water under extremely mild and environmentally benign conditions giving a 1:1 mixture of diastereoselectively (2R,4S)- and (2S,4S)-2-aryl- or 2-alkyl-tetrahydropyranois in high yields. (c) 2008 Published by Elsevier Ltd.