H-Glu-Gly-Phe-OH

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: H-Glu-Gly-Phe-OH
• 英文别名: (4S)-4-amino-5-[[2-[[(1S)-1-carboxy-2-phenylethyl]amino]-2-oxoethyl]amino]-5-oxopentanoic acid
• 化学式: C₁₆H₂₁N₃O₆
• mdl: MFCD00037266
• 分子量: 351.35
• InChiKey: ZWQVYZXPYSYPJD-RYUDHWBXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.3
• 重原子数：
  25
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.375
• 拓扑面积：
  159
• 氢给体数：
  5
• 氢受体数：
  7

文献信息

• Antigenic materials
  申请人：COUNCIL OF GOVERNORS OF THE UNITED MEDICAL AND DENTAL SCHOOLS OF GUY'S AND ST. THOMAS'S HOSPITALS

  公开号：EP0116472A2

  公开（公告）日：1984-08-22

  An antigenic material having a molecular weight of 3800-4500, and useful in the preparation of an anticaries vaccine is produced from a known antigenic material, antigen I/II of molecular weight 185,000 daltons obtained from the culture supernatant of Streptococcus mutans. The smaller molecular weight fraction of the invention contains the same antigenic determinants as the known 185,000 dalton material but the lower molecular weight material can be used with less side effects. The antigenic material can be used for the production of vaccine preparations that could be administered parentally or by topical application to the gums.

  一种分子量为 3800-4500 的抗原材料可用于制备抗龋齿疫苗，它是由已知的抗原材料，即从变异链球菌培养上清液中获得的分子量为 185,000 道尔顿的抗原 I/II 制成的。本发明中分子量较小的部分含有与已知的 185,000 道尔顿材料相同的抗原决定簇，但使用分子量较低的材料可减少副作用。这种抗原材料可用于生产疫苗制剂，这种疫苗制剂可用于亲体给药或局部涂抹牙龈。
• ENZYMATIC ESTER HYDROLYSIS
  申请人：Quaedflieg Peter Jan Leonard Mario

  公开号：US20100311130A1

  公开（公告）日：2010-12-09

  The present invention relates to a method for selectively hydrolysing a pendant ester bond formed by an unsubstituted or substituted hydrocarbon group—optionally comprising one or more heteroatoms—and a pendant carboxylate moiety, which carboxylate moiety is part of a polymer or a polymerisable compound, which polymer or polymerisable compound comprises at least one other hydrolysable group, wherein the method comprises contacting the polymer or polymerisable compound with a hydrolytic enzyme.
• US4594244A
  申请人：——

  公开号：US4594244A

  公开（公告）日：1986-06-10