2-[(4-Azaniumyl-4-carboxybutanoyl)amino]ethanesulfonate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[(4-Azaniumyl-4-carboxybutanoyl)amino]ethanesulfonate
• 化学式: C7H14N2O6S
• 分子量: 254.26
• InChiKey: WGXUDTHMEITUBO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.9
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  155
• 氢给体数：
  4
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  N-邻苯二甲酰-L-谷氨酸酐 、 牛磺酸 生成 2-[(4-Azaniumyl-4-carboxybutanoyl)amino]ethanesulfonate
  参考文献：
  名称：

  FURKA, ARPAD;GYLYAS, JOZSEF X. SEBESTYEN FERENC

  摘要：

  DOI：

文献信息

• Glutaurine compositions and therapeutic uses thereof
  申请人：ThermoLife International, LLC

  公开号：US10420739B1

  公开（公告）日：2019-09-24

  The present disclosure provides compositions and methods useful for the treatment of a body weight condition or a thyroid disorder. The compositions induces increased T3 levels while preventing thyroidal atrophy. Also provided are compositions and methods for the treatment of a disease or condition that is estrogen sensitive, estrogen receptor dependent or estrogen receptor mediated such as breast cancer.

  本公开提供了用于治疗体重状况或甲状腺疾病的组合物和方法。这些组合物在防止甲状腺萎缩的同时，还能诱导T3水平的升高。还提供了用于治疗雌激素敏感、雌激素受体依赖或雌激素受体介导的疾病或病症（如乳腺癌）的组合物和方法。
• Substituted glutaurine compounds and substituted glutaurine derivatives
  申请人：ThermoLife International, LLC

  公开号：US10471032B1

  公开（公告）日：2019-11-12

  The present disclosure provides compounds, compositions, and dietary supplements useful for the treatment of a body weight condition or a thyroid disorder. The compounds induce increased T3 levels while preventing thyroidal atrophy. Also provided are compounds, compositions, and dietary supplements useful for the treatment of a disease or condition that is estrogen sensitive, estrogen receptor dependent or estrogen receptor mediated such as breast cancer.

  本公开提供了可用于治疗体重状况或甲状腺疾病的化合物、组合物和膳食补充剂。这些化合物在防止甲状腺萎缩的同时，还能诱导T3水平的升高。本发明还提供了用于治疗雌激素敏感、雌激素受体依赖或雌激素受体介导的疾病或病症（如乳腺癌）的化合物、组合物和膳食补充剂。
• Synthesis and composition of photodynamic therapeutic agents for the targeted treatment of cancer
  申请人：On Target Laboratories, LLC

  公开号：US10676487B2

  公开（公告）日：2020-06-09

  The present invention describes new compounds that are useful for image-guided surgery and photodynamic therapy. In particular the compounds may be targeted to the nucleus or the mitochondria after compounds were delivered to diseased tissues such as cancer using a ligand that target receptor that express on the diseased tissue and followed by receptor mediated endocytosis and provide effective activity against cancer cells as well as other disorders. Methods and compositions for use of the same are described.

  本发明描述了可用于图像引导手术和光动力疗法的新型化合物。 特别是，这些化合物可通过使用针对病变组织上表达的受体的配体，然后通过受体介导的内吞作用，将化合物递送至病变组织（如癌症）后靶向作用于细胞核或线粒体，并对癌细胞和其他疾病提供有效的活性。 本文还介绍了使用这些配体的方法和组合物。
• Aminoalkanesulfonic acid derivatives and pharmaceutical compositions for use in preventing or treating heart diseases
  申请人：NIPPON ZOKI PHARMACEUTICAL CO. LTD.

  公开号：EP0467856B1

  公开（公告）日：1997-03-19
• JP2003321357A
  申请人：——

  公开号：JP2003321357A

  公开（公告）日：2003-11-11