1-(2-Amino-3-phenylpropanoyl)-4-hydroxypyrrolidine-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1-(2-Amino-3-phenylpropanoyl)-4-hydroxypyrrolidine-2-carboxylic acid
• 化学式: C₁₄H₁₈N₂O₄
• 分子量: 278.3
• InChiKey: WJSNJMXOBDSZDL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.3
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  104
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Hyaluronic acid production promoting agent
  申请人：Pharma Foods International Co., Ltd.

  公开号：US11179424B2

  公开（公告）日：2021-11-23

  An agent of the present invention comprising poultry feet or a processed product thereof, preferably a hydrolysate of an extract of poultry feet, promotes hyaluronic acid production, thereby exhibiting excellent effects of preventing or treating a joint disorder, improving skin dryness, wrinkles or skin tension, moisturizing the skin, etc. The agent is thus useful as a medicament, a quasi-drug, a cosmetic product, a food product or an animal feed.

  本发明的制剂包含家禽脚或其加工产品，最好是家禽脚提取物的水解物，可促进透明质酸的产生，从而在预防或治疗关节疾病、改善皮肤干燥、皱纹或皮肤紧张、滋润皮肤等方面表现出卓越的效果。因此，该制剂可用作药物、准药物、化妆品、食品或动物饲料。
• COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS
  申请人：Beiersdorf AG

  公开号：EP2117536A2

  公开（公告）日：2009-11-18
• HYALURONIC ACID PRODUCTION PROMOTING AGENT
  申请人：Pharma Foods International Co., Ltd.

  公开号：US20180036350A1

  公开（公告）日：2018-02-08

  An agent of the present invention comprising poultry feet or a processed product thereof, preferably a hydrolysate of an extract of poultry feet, promotes hyaluronic acid production, thereby exhibiting excellent effects of preventing or treating a joint disorder, improving skin dryness, wrinkles or skin tension, moisturizing the skin, etc. The agent is thus useful as a medicament, a quasi-drug, a cosmetic product, a food product or an animal feed.
• [EN] COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS<br/>[FR] APPLICATIONS COSMÉTIQUES ET PHARMACEUTIQUES D'ACIDES AMINÉS N-ACYLÉS, ET COMPOSÉS STRUCTURELLEMENT APPARENTÉS
  申请人：BEIERSDORF AG

  公开号：WO2008101693A2

  公开（公告）日：2008-08-28

  [EN] Disclosed are cosmetic and pharmaceutical applications of N-acylated amino acids and structurally related compounds and in particular, the use of N-acylated amino acids and structurally related compounds for inhibiting the glycation of proteins in a living organism.
  [FR] L'invention porte sur des applications cosmétiques et pharmaceutiques d'acides aminés N-acylés, et sur des composés structurellement apparentés, et en particulier sur l'utilisation de ces acides aminés N-acylés, et composés structurellement parents pour inhiber la glycation de protéines dans un organisme vivant.