2-(2,7-Bis{[bis(carboxymethyl)amino]methyl}-6-hydroxy-3-oxo-3h-xanthen-9-yl)benzoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-(2,7-Bis{[bis(carboxymethyl)amino]methyl}-6-hydroxy-3-oxo-3h-xanthen-9-yl)benzoic acid
• 英文别名: 2-[2,7-bis[[bis(carboxymethyl)amino]methyl]-3-hydroxy-6-oxoxanthen-9-yl]benzoic acid
• 化学式: C₃₀H₂₆N₂O₁₃
• 分子量: 622.5
• InChiKey: XIAYFENBYCWHGY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.1
• 重原子数：
  45
• 可旋转键数：
  14
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  240
• 氢给体数：
  6
• 氢受体数：
  15

文献信息

• Fluorescently Labeled Calcium Phosphate Surfaces
  申请人：Rao Hongwei Hanna

  公开号：US20110294151A1

  公开（公告）日：2011-12-01

  Described herein are substrates composed of a base coated with a fluorophore-labeled calcium phosphate coating. The substrates are useful in culturing and studying the activity of a variety of cells. The substrates described herein can be used for both solution- and image-based analysis of cultured cells. New methods for producing and using such coated substrates are also disclosed.

  本文描述了一种由基底涂覆有荧光标记的磷酸钙涂层的基板。这些基板在培养和研究各种细胞的活动方面非常有用。这些基板可用于培养细胞的溶液和图像分析。还公开了生产和使用这种涂层基板的新方法。
• Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1A (JARID1A) and 1B (JARID1B) Histone Demethylase
  申请人：Yale University

  公开号：US20150272939A1

  公开（公告）日：2015-10-01

  The present invention includes a novel high-throughput screen capable of identifying compounds that inhibit JARID1B demethylase activity or JARID1A demethylase activity. The present invention further includes novel inhibitors of JARID1B demethylase activity and/or JARID1A demethylase activity, and methods using the same.