2-(hexadecanoylamino)-3-(1H-indol-3-yl)propanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-(hexadecanoylamino)-3-(1H-indol-3-yl)propanoic acid
• 化学式: C₂₇H₄₂N₂O₃
• 分子量: 442.6
• InChiKey: YFPVRCYDDXYINM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  32
• 可旋转键数：
  18
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  82.2
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• COMPOSITION FOR TREATING ATOPY OR PRURITUS COMPRISING N-ACETYL OR N-ACYL AMINO ACID
  申请人：Stemdr Inc.

  公开号：EP3714880A2

  公开（公告）日：2020-09-30

  The present disclosure relates to a composition for preventing, alleviating or treating pruritus and/or atopy using an N-acetylamino acid or an N-acylamino acid having almost no side effects on the human body. Also, the present disclosure relates to a cosmetic composition for moisturizing skin or soothing skin. The composition of the present disclosure may be utilized to ameliorate a problematic skin condition caused by various causes, or to safely and effectively alleviate or treat pruritus and/or atopy without concern about side effects.

  本公开涉及一种使用对人体几乎无副作用的 N-乙酰基氨基酸或 N-酰基氨基酸来预防、减轻或治疗皮肤瘙痒症和/或过敏症的组合物。此外，本公开还涉及一种用于滋润皮肤或舒缓皮肤的化妆品组合物。本公开的组合物可用于改善由各种原因引起的皮肤问题，或安全有效地缓解或治疗皮肤瘙痒症和/或过敏症，而无需担心副作用。
• AN ENZYME-CATALYZED PROCESS FOR PREPARING N-ACYL AMINO ACIDS AND N-ACYL AMINO ACID AMIDES
  申请人：NOVO NORDISK A/S

  公开号：EP0473700A1

  公开（公告）日：1992-03-11
• PEPTIDE LUNG SURFACTANTS AND THERAPEUTIC COMBINATIONS
  申请人：MERRELL PHARMACEUTICALS INC.

  公开号：EP0656902B1

  公开（公告）日：1997-12-17
• TRYPTOPHANYLESTER UND DEREN N-ACYL-DERIVATE ZUR PRÄVENTION UND THERAPIE VON ERKRANKUNGEN, DIE DURCH OXIDATIONSPROZESSE VERURSACHT ODER VERSTÄRKT WERDEN
  申请人：Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.

  公开号：EP1113795B1

  公开（公告）日：2005-07-13
• COMPOSITION FOR TREATING ATOPY OR PRURITUS CONTAINING N-ACETYL OR N-ACYLAMINO ACID
  申请人：STEMDR INC.

  公开号：US20200316001A1

  公开（公告）日：2020-10-08

  The present disclosure relates to a composition for preventing, alleviating or treating pruritus and/or atopy using an N-acetylamino acid or an N-acylamino acid having almost no side effects on the human body. Also, the present disclosure relates to a cosmetic composition for moisturizing skin or soothing skin. The composition of the present disclosure may be utilized to ameliorate a problematic skin condition caused by various causes, or to safely and effectively alleviate or treat pruritus and/or atopy without concern about side effects.