α-aspartyl-phenylalanine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: α-aspartyl-phenylalanine
• 英文别名: aspartame；alpha-Aspartylphenylalanine；3-amino-4-[(1-carboxy-2-phenylethyl)amino]-4-oxobutanoic acid
• 化学式: C₁₃H₁₆N₂O₅
• 分子量: 280.28
• InChiKey: YZQCXOFQZKCETR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.3
• 重原子数：
  20
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  130
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  α-aspartyl-phenylalanine 生成 2-[(2-Amino-4-methoxy-4-oxobutanoyl)amino]-3-phenylpropanoic acid
  参考文献：
  名称：

  MITA, RYUITI;KATO, TOSIO;XIGUTI, TEDZIRO;OURA, TAKEHSI;YAMAGUTI, AKIXIRO

  摘要：

  DOI：

文献信息

• ANTIBIOFILM GLYCOPEPTIDES
  申请人：Reynolds Eric Charles

  公开号：US20120283174A1

  公开（公告）日：2012-11-08

  The present invention relates to peptides and compositions that have antibiofilm properties. In particular, the peptides and compositions of the invention can be used for the treatment or prevention of various conditions including dental caries, gingivitis, periodontitis, oral mucositis, dry mouth and xerostomia.

  本发明涉及具有抗生物膜特性的肽和组合物。具体而言，本发明的肽和组合物可用于治疗或预防各种疾病，包括龋齿、牙龈炎、牙周炎、口腔粘膜炎、口干和口腔干燥。
• [EN] TASTE MODULATING ALDEHYDES<br/>[FR] ALDÉHYDES MODULANT LE GOÛT
  申请人：TAKASAGO INT CORPORATION USA

  公开号：WO2018049352A1

  公开（公告）日：2018-03-15

  Aldehydes of formula (I) (X represents an alkyl or alkenyl group having up to 9 carbon atoms) for use in taste modulation and/or flavor compositions are provided. Specifically, the compounds of the presently disclosed subject matter provide effective and unexpected taste modulating properties. The taste modulation and/or flavor compositions can be incorporated into various consumer end products in particular in combination with high intensity sweeteners.

  提供化学式为(I)的醛类化合物（其中X代表含有最多9个碳原子的烷基或烯基基团），用于口感调节和/或风味组合。具体而言，本发明的化合物提供了有效和意外的口感调节特性。口感调节和/或风味组合物可以与高强度甜味剂结合，被纳入到各种消费者终端产品中。
• CYCLIC SULFONIUM SALT, METHOD FOR PRODUCTION OF CYCLIC SULFONIUM SALT, AND GLYCOSIDASE INHIBITOR
  申请人：Muraoka Osamu

  公开号：US20100063302A1

  公开（公告）日：2010-03-11

  Disclosed are: kotalanol which has an inhibitory activity on a glucosidase; a method for producing kotalanol or a cyclic sulfonium salt which is an analogue to kotalanol by an organic synthesis technique; a cyclic sulfonium salt produced by the method; a glucosidase inhibitor comprising the compound; an anti-diabetic agent or an anti-diabetic food comprising the glucosidase inhibitor. A sulfonium compound including kotalanol can be produced by coupling a thio-sugar synthesized from D-xylose (e.g., a compound having a cyclic structure composed of 4 carbon atoms and one sulfur atom, such as 1,4-dideoxy-1,4-epithio-D-arabinitol) with a heptitol cyclic sulfate ester having a protected hydroxyl group and synthesized from a pentose (D-xylose, D-ribose, D-arabinose, D-lyxose, L-xylose, L-ribose, L-arabinose or L-lyxose) to produce a cyclic sulfonium salt having a protected hydroxyl group, and then deprotecting the hydroxyl group.

  本发明涉及一种对葡萄糖苷酶具有抑制活性的kotalanol；一种通过有机合成技术制备kotalanol或类似kotalanol的环状亚磺酸盐的方法；一种通过该方法制备的环状亚磺酸盐；一种包含该化合物的葡萄糖苷酶抑制剂；一种包含该葡萄糖苷酶抑制剂的抗糖尿病剂或抗糖尿病食品。可以通过将从D-木糖合成的硫代糖（例如，由4个碳原子和1个硫原子组成的环状结构化合物，如1,4-二去氧-1,4-环硫-D-阿拉伯糖醇）与从戊糖（D-木糖，D-核糖，D-阿拉伯糖，D-吕氏木糖，L-木糖，L-核糖，L-阿拉伯糖或L-吕氏木糖）合成的带有保护羟基的庚糖环硫酸酯偶联，以制备具有保护羟基的环状亚磺酸盐，然后去保护羟基来制备包含kotalanol的亚磺酸化合物。
• Water-absorbing material and absorbent article employing the same
  申请人：——

  公开号：US20030045198A1

  公开（公告）日：2003-03-06

  The water absorbent material of the present invention is composed of a copolymer of an anhydropolyamino acid having at least one ethylenically unsaturated double bond in a molecule, a water-soluble monomer having an ethylenically unsaturated double bond and polysaccharides, and has high water absorption ratio and high water absorption rate in pure water or water having a low ion content and also has high absorption properties for high concentration salt-containing solutions.

  本发明的吸水材料由至少在分子中具有一个乙烯基不饱和双键的无水多氨基酸共聚物、具有乙烯基不饱和双键的水溶性单体和多糖组成，具有高吸水比和高吸水速率，在纯水或低离子含量的水中具有高吸收性能，并且对高浓度盐含量的溶液也具有高吸收性能。
• Water absorbent material and absorbent article using same
  申请人：Tanaka Hisakazu

  公开号：US20050171309A1

  公开（公告）日：2005-08-04

  The water absorbent material of the present invention is composed of a copolymer of an anhydropolyamino acid having at least one ethylenically unsaturated double bond in a molecule, a water-soluble monomer having an ethylenically unsaturated double bond and polysaccharides, and has high water absorption ratio and high water absorption rate in pure water or water having a low ion content and also has high absorption properties for high concentration salt-containing solutions.

  本发明的吸水材料由至少含有一个分子内乙烯基不饱和双键的无水多聚氨基酸共聚物、含有乙烯基不饱和双键的水溶性单体和多糖组成，具有在纯水或低离子含量的水中高吸水率和高吸水速率，并且对高浓度含盐溶液具有高吸收性能。